Epidemiology of genital papillomaviruses and cervical cancer.

Epidemiology of genital papillomaviruses and cervical cancer.
复制标题

生殖器乳头瘤病毒和宫颈癌的流行病学。

DOI:
10.1093/clinids/11.3.426
复制
发表时间:
1989
期刊:
Reviews of infectious diseases
影响因子:
--
通讯作者:
Brinton,LA
Brinton,LA
中科院分区:
--
文献类型:
--
作者:
Reeves,WC;Rawls,WE;Brinton,LA

文献摘要

参考文献

被引文献

相似文献

子宫颈癌是一种极为常见的疾病。它的自然历史已经被很好地描述,并且个体的危险因素已经被定义。从流行病学证据可以清楚地看出,宫颈癌的病因是多因素的,涉及性传播媒介(如生殖器乳头状瘤病毒)的感染以及诸如怀孕、吸烟、使用激素避孕药和饮食等辅助因素。证据暗示乳头瘤病毒作为宫颈癌的病原是来自各种观察性实验室研究。生殖器乳头瘤病毒引起发育不良病变。大多数侵袭性宫颈癌含有乳头瘤病毒DNA,从宫颈癌衍生的细胞系也是如此。病毒DNA似乎整合到细胞DNA中,整合涉及病毒DNA中高度保守的转录活跃区域。
Cervical cancer is an extremely common disease. Its natural history has been well described, and individual risk factors have been defined. It is clear from the epidemiologic evidence that cervical cancer has a multifactorial etiology involving infection with sexually transmitted agents such as genital papillomaviruses and cofactors such as pregnancy, smoking, use of hormonal contraceptives, and diet. The evidence implicating papillomavirus as an etiologic agent of cervical cancer has come from a variety of observational laboratory studies. Genital papillomaviruses induce dysplastic lesions. Most invasive cervical cancers contain papillomavirus DNA, as do cell lines derived from cervical cancers. Viral DNA appears to be integrated into cellular DNA, and integration involves highly conserved, transcriptionally active regions of the viral DNA.
乳头瘤病毒基因表达的细胞控制缺陷导致人类生殖器癌持续病毒感染的细胞内监测
DOI: --
发表时间: 1986
期刊: The Lancet
影响因子: --
作者:
H. Hausen
通讯作者: H. Hausen
宫颈癌流行病学中的饮食和吸烟。
DOI: --
发表时间: 1983
期刊: Journal of the National Cancer Institute
影响因子: --
作者:
Marshall,JR;Graham,S;Byers,T;Swanson,M;Brasure,J
通讯作者: Brasure,J
DOI: 10.1159/000132342
发表时间: 1987
期刊: Cytogenetics and cell genetics
影响因子: --
作者:
N. Popescu;J. DiPaolo;S. Amsbaugh
通讯作者: N. Popescu;J. DiPaolo;S. Amsbaugh
DOI: --
发表时间: 1973
期刊: Journal of the American Medical Association (JAMA)
影响因子: --
作者:
N. Whitehead;F. Reyner;J. Lindenbaum
通讯作者: J. Lindenbaum
一种与宫颈癌相关的新型乳头瘤病毒。
DOI: 10.1016/0042-6822(87)90366-7
发表时间: 1987
期刊: Virology
影响因子: 3.7
作者:
Lorincz,AT;Quinn,AP;Lancaster,WD;Temple,GF
通讯作者: Temple,GF