Fast temperature measurement following single laser-induced cavitation inside a microfluidic gap.
Fast temperature measurement following single laser-induced cavitation inside a microfluidic gap.
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DOI:
10.1038/srep05445
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发表时间:
2014-06-25
影响因子:
4.6
通讯作者:
Ohl CD
中科院分区:
文献类型:
--
作者:
Quinto-Su PA;Suzuki M;Ohl CD
Single transient laser-induced microbubbles have been used in microfluidic chips for fast actuation of the liquid (pumping and mixing), to interact with biological materials (selective cell destruction, membrane permeabilization and rheology) and more recenty for medical diagnosis. However, the expected heating following the collapse of a microbubble (maximum radius ~ 10–35 µm) has not been measured due to insufficient temporal resolution. Here, we extend the limits of non-invasive fluorescence thermometry using high speed video recording at up to 90,000 frames per second to measure the evolution of the spatial temperature profile imaged with a fluorescence microscope. We found that the temperature rises are moderate (< 12.8°C), localized (< 15 µm) and short lived (< 1.3 ms). However, there are significant differences between experiments done in a microfluidic gap and a container unbounded at the top, which are explained by jetting and bubble migration. The results allow to safe-guard some of the current applications involving laser pulses and photothermal bubbles interacting with biological material in different liquid environments.
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影响因子:
6.1
作者:
Le Gac, Severine;Zwaan, Ed;Ohl, Claus-Dieter
通讯作者:
Ohl, Claus-Dieter
影响因子:
3.4
作者:
Pitsillides, CM;Joe, EK;Lin, CP
通讯作者:
Lin, CP
DOI:
10.1007/bf00324952
发表时间:
1989-12-01
期刊:
APPLIED PHYSICS B-PHOTOPHYSICS AND LASER CHEMISTRY
影响因子:
--
作者:
ROMANO, V;ZWEIG, AD;WEBER, HP
通讯作者:
WEBER, HP
影响因子:
3.9
作者:
Lai, Hsuan-Hong;Quinto-Su, Pedro A.;Allbritton, Nancy L.
通讯作者:
Allbritton, Nancy L.
影响因子:
6.1
作者:
Dijkink, Rory;Ohl, Claus-Dieter
通讯作者:
Ohl, Claus-Dieter