Metaorganisms as the new frontier.

Metaorganisms as the new frontier.
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DOI:
10.1016/j.zool.2011.04.001
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发表时间:
2011-09
期刊:
影响因子:
2
通讯作者:
McFall-Ngai, Margaret J.
McFall-Ngai, Margaret J.
中科院分区:
生物学3区
文献类型:
--
作者:
Bosch, Thomas C. G.;McFall-Ngai, Margaret J.

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因为几乎所有的生物体都是一个相互依赖的元生物体的一部分,所以了解宿主-微生物物种之间的潜在联系及其进化和分子基础已经成为动物学的新前沿。新的高通量测序方法的可用性以及概念上的理解,即进步主要源于传统学科边界的交叉点,使生物学家能够剖析控制物种相互依赖关系的机制。在这篇观点文章中,我们概述了物种间相互作用的一些问题,提出了两个案例研究,阐明了在解决复杂和基本的动物学问题时界面研究的必要性,并表明,一个跨学科的方法,旨在了解共同进化的多物种关系将连接基因组,表型,生态系统和进化力量,塑造了他们。我们希望这篇文章能激发其他类似性质的合作,对通常被称为“动物学”的多样化景观。
Because it appears that almost all organisms are part of an interdependent meta-organism, an understanding of the underlying host-microbe species associations, and of its evolution and molecular underpinnings, has become the new frontier in zoology. The availability of novel highthroughput sequencing methods together with the conceptual understanding that advances mostly originate at the intersection of traditional disciplinary boundaries, enable biologists to dissect the mechanisms that control the interdependent associations of species. In this perspective article, we outline some of the issues in interspecies interactions, present two case studies illuminating the necessity of interfacial research when addressing complex and fundamental zoological problems, and show that an interdisciplinary approach that seeks to understand co-evolved multi-species relationships will connect genomes, phenotypes, ecosystems and the evolutionary forces that have shaped them. We hope that this article inspires other collaborations of a similar nature on the diverse landscape commonly referred to as “zoology”.
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