Epidemiology and cost of nosocomial gastroenteritis, Avon, England, 2002-2003.

Epidemiology and cost of nosocomial gastroenteritis, Avon, England, 2002-2003.
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DOI:
10.3201/eid1010.030941
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发表时间:
2004-10
影响因子:
11.8
通讯作者:
Sarangi J
Sarangi J
中科院分区:
医学2区
文献类型:
--
作者:
Lopman BA;Reacher MH;Vipond IB;Hill D;Perry C;Halladay T;Brown DW;Edmunds WJ;Sarangi J

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迅速实施控制措施可能对控制胃肠炎爆发有效。卫生保健相关的胃肠炎爆发是一个日益认识到的问题,但缺乏这些事件的流行病学的详细知识。我们在2002年至2003年积极监测英格兰三家医院系统的胃肠炎爆发。在227个单位爆发(1.33次爆发/单位年)中,共有2,154名患者(2.21例/1,000住院日)和1,360名医护人员(0.47例/1,000住院日)受到影响。诺如病毒,在63%的爆发中检测到,是主要的病原体。限制新的入院受影响的单位导致5 443个损失的床日。损失的床位天数加上工作人员缺勤的费用计算为635,000英镑(美元1.01每1,000张病床的平均死亡人数为1,000万人。根据我们的推断,胃肠炎的爆发可能会使英国国民健康服务体系损失1.15亿英镑(美元)。2002年至2003年,当医院对新入院者迅速关闭(<4天)时,暴发控制得更快(7.9对15.4天,p = 0.0023)。迅速实施控制措施可能对控制暴发有效。
Implementing control measures rapidly may be effective in controlling gastroenteritis outbreaks. Healthcare-associated outbreaks of gastroenteritis are an increasingly recognized problem, but detailed knowledge of the epidemiology of these events is lacking. We actively monitored three hospital systems in England for outbreaks of gastroenteritis in 2002 to 2003. A total of 2,154 patients (2.21 cases/1,000-hospital-days) and 1,360 healthcare staff (0.47 cases/1,000-hospital-days) were affected in 227 unit outbreaks (1.33 outbreaks/unit-year). Norovirus, detected in 63% of outbreaks, was the predominant etiologic agent. Restricting new admissions to affected units resulted in 5,443 lost bed-days. The cost of bed-days lost plus staff absence was calculated to be £635,000 (U.S.$ 1.01 million) per 1,000 beds. By our extrapolation, gastroenteritis outbreaks likely cost the English National Health Service £115 million (U.S.$ 184 million) in 2002 to 2003. Outbreaks were contained faster (7.9 vs. 15.4 days, p = 0.0023) when units were rapidly closed to new admissions (<4 days). Implementing control measures rapidly may be effective in controlling outbreaks.
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