Physical Activity, Sedentary Behavior, Cardiorespiratory Fitness and Metabolic Syndrome in Adolescents: Systematic Review and Meta-Analysis of Observational Evidence.

Physical Activity, Sedentary Behavior, Cardiorespiratory Fitness and Metabolic Syndrome in Adolescents: Systematic Review and Meta-Analysis of Observational Evidence.
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DOI:
10.1371/journal.pone.0168503
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发表时间:
2016
期刊:
影响因子:
3.7
通讯作者:
Guedes DP
Guedes DP
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Oliveira RG;Guedes DP

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代谢综合征(MetS)已在青少年中被诊断出来,相关因素包括低水平的身体活动,长期久坐不动的行为和低心肺功能。然而,特别是在青少年中,研究提出了相互矛盾的结果。本研究的目的是对观察性研究进行系统回顾和荟萃分析,以了解青少年体力活动、久坐行为、心肺功能和代谢综合征之间的关系。在数据库PubMed、SPORTDiscus、LILACS和科克伦图书馆中进行检索。对于荟萃分析,计算比值比(OR)以及相应的置信区间(95% CI),其中通过二分数据(暴露变量)分析效应指标,MetS用作事件。18项研究被纳入荟萃分析。初步分析表明,低水平的体力活动(OR = 1.35 [1.03 - 1.79]; p = 0.03)和低心肺功能(OR = 4.05 [2.09 ~ 7.87]; p < 0.01)与MetS的发展显著相关,而对于久坐行为,以屏幕时间> 2小时/天为代表,未发现显著相关性(OR = 1.20 [0.91 - 1.59]; p = 0.20)。亚组分析表明,低体力活动与代谢综合征之间的关联依赖于加速度计技术的使用(OR = 2.93 [1.56至5.47]; p < 0.01)。筛查时间> 2小时/天仅在周末与MetS显著相关(OR = 2.05 [1.13至3.73]; p = 0.02)。关于心肺适应性,与代谢综合征的显着关联被发现独立的最大摄氧量(VO 2 max)测量方法。低水平的体力活动,低指数的心肺功能和久坐不动的行为,表现为屏幕时间> 2小时/天,在周末,与代谢综合征的发展在青春期显着相关。
Metabolic syndrome (MetS) has been diagnosed in adolescents and among the associated factors are low levels of physical activity, sedentary behavior over long periods and low cardiorespiratory fitness. However, specifically in adolescents, studies present conflicting results. The aim of the present study was to conduct a systematic review and meta-analysis of observational studies, in order to map the association between physical activity, sedentary behavior, cardiorespiratory fitness and MetS in adolescents. A search was performed in the databases PubMed, SPORTDiscus, LILACS and the Cochrane Library. For the meta-analysis, the odds ratio (OR) was calculated together with the respective confidence intervals (95% CI), in which the measures of effect were analyzed by dichotomous data (exposure variables) with MetS used as events. Eighteen studies were included in the meta-analysis. Primary analysis demonstrated that low levels of physical activity (OR = 1.35 [1.03 to 1.79]; p = 0.03) and low cardiorespiratory fitness (OR = 4.05 [2.09 to 7.87]; p < 0.01) were significantly associated with the development of MetS, while for sedentary behavior, represented by screen time > 2 hours/day, a significant association was not identified (OR = 1.20 [0.91 to 1.59]; p = 0.20). Subgroup analyses demonstrated that the association between low physical activity and MetS was dependent on the use of the accelerometry technique (OR = 2.93 [1.56 to 5.47]; p < 0.01). Screen time > 2 hours/day was significantly associated with MetS only on weekends (OR = 2.05 [1.13 to 3.73]; p = 0.02). With respect to cardiorespiratory fitness, a significant association with MetS was found independent of the maximal oxygen uptake (VO2max) measurement method. Low levels of physical activity, low indices of cardiorespiratory fitness and sedentary behavior, represented by screen time > 2 hours/day on weekends, were significantly associated with the development of MetS in adolescence.
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