Message in a Bubble: Shuttling Small RNAs and Proteins Between Cells and Interacting Organisms Using Extracellular Vesicles.
Message in a Bubble: Shuttling Small RNAs and Proteins Between Cells and Interacting Organisms Using Extracellular Vesicles.
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气泡中的消息:使用细胞外囊泡在细胞和相互作用的生物之间穿梭小RNA和蛋白质。
DOI:
10.1146/annurev-arplant-081720-010616
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发表时间:
2021-06-17
影响因子:
23.9
通讯作者:
Jin H
中科院分区:
文献类型:
--
作者:
Cai Q;He B;Wang S;Fletcher S;Niu D;Mitter N;Birch PRJ;Jin H
Communication between plant cells and interacting microorganisms requires the secretion and uptake of functional molecules to and from the extracellular environment and is essential for the survival of both plants and their pathogens. Extracellular vesicles (EVs) are lipid bilayer–enclosed spheres that deliver RNA, protein, and metabolite cargos from donor to recipient cells and participate in many cellular processes. Emerging evidence has shown that both plant and microbial EVs play important roles in cross-kingdom molecular exchange between hosts and interacting microbes to modulate host immunity and pathogen virulence. Recent studies revealed that plant EVs function as a defense system by encasing and delivering small RNAs (sRNAs) into pathogens, thereby mediating cross-species and cross-kingdom RNA interference to silence virulence-related genes. This review focuses on the latest advances in our understanding of plant and microbial EVs and their roles in transporting regulatory molecules, especially sRNAs, between hosts and pathogens. EV biogenesis and secretion are also discussed, as EV function relies on these important processes.
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影响因子:
7.3
作者:
Andreu Z;Yáñez-Mó M
通讯作者:
Yáñez-Mó M
DOI:
10.1038/nrmicro3480
发表时间:
2015-10
期刊:
Nature reviews. Microbiology
影响因子:
--
作者:
Brown L;Wolf JM;Prados-Rosales R;Casadevall A
通讯作者:
Casadevall A
影响因子:
3.4
作者:
An, QL;Hückelhoven, R;Van Bel, AJE
通讯作者:
Van Bel, AJE
影响因子:
3.5
作者:
Bahar, Ofir;Mordukhovich, Gideon;Ronald, Pamela C.
通讯作者:
Ronald, Pamela C.
影响因子:
5.6
作者:
Bleackley, Mark;Samuel, Monisha;Anderson, Marilyn A.
通讯作者:
Anderson, Marilyn A.