Ethnic differences in post-menopausal plasma oestrogen levels: high oestrone levels in Japanese-American women despite low weight.
Ethnic differences in post-menopausal plasma oestrogen levels: high oestrone levels in Japanese-American women despite low weight.
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绝经后等离子体雌激素水平的种族差异：尽管体重较低，但日本女性的雌激素水平较高。
DOI：
10.1054/bjoc.1999.1082
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发表时间：
2000-06
影响因子：
8.8
通讯作者：
Henderson, BE
中科院分区：
文献类型：
--
作者：
Probst-Hensch, NM;Pike, MC;McKean-Cowdin, R;Stanczyk, FZ;Kolonel, LN;Henderson, BE
日裔美国妇女的乳腺癌发病率正在接近美国白人。我们调查了这一转变是否与两个民族相似的绝经后血浆激素水平有关。我们还纳入了非裔美国人和拉丁裔女性，以进一步了解雌激素代谢可能存在的种族差异。我们测量了30名日裔美国人、39名非拉丁裔白人（“白人”）、66名非裔美国人和58名拉丁裔女性的雄烯二酮(A)、雌酮（E1）和雌二醇（E2）。（年龄调整）几何平均E1水平在日裔美国人中为34 pg ml - 1，在白人中为28 pg ml - 1，在非洲裔美国人中为35 pg ml - 1，在拉丁美洲人中为31 pg ml - 1。调整体重指数后，日裔美国人的E1均值在所有组中最高，且显著高于白人（p = 0.05）。几何平均A浓度在日裔美国人中也最高。E2水平的种族差异不大。总之，日裔美国妇女绝经后血浆雌激素水平至少和白人一样高。©2000癌症研究运动
Breast cancer incidence in Japanese-American women is approaching that of US Whites. We investigated whether this shift is paralleled by similar post-menopausal plasma hormone levels in the two ethnic groups. We also included African-American and Latina women to further our understanding of possible ethnic differences in oestrogen metabolism. We measured androstenedione (A), oestrone (E1) and oestradiol (E2) in 30 Japanese-American, 39 non-Latina White (‘White’), 66 African-American and 58 Latina women. The (age-adjusted) geometric mean E1 levels were 34 pg ml−1in Japanese-Americans, 28 pg ml−1in Whites, 35 pg ml−1in African-Americans and 31 pg ml−1in Latinas. After adjustment for body mass index, Japanese-Americans had the highest mean E1 value of all groups and this was statistically significantly greater than the value for Whites (Pt-test= 0.05). The geometric mean A concentrations were also highest in Japanese-Americans. There was little ethnic difference in E2 levels. In conclusion, post-menopausal plasma oestrogen levels in Japanese-American women are at least as high as those in Whites. © 2000 Cancer Research Campaign
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DOI：
10.1016/0002-9378(92)91617-j
发表时间：
1992-05-01
影响因子：
9.8
作者：
CASSIDENTI, DL;PIKE, MC;LOBO, RA
通讯作者：
LOBO, RA
影响因子：
7.1
作者：
GOLDIN, BR;ADLERCREUTZ, H;GERSHOFF, SN
通讯作者：
GERSHOFF, SN
影响因子：
8.8
作者：
SHIMIZU, H;ROSS, RK;HENDERSON, BE
通讯作者：
HENDERSON, BE
影响因子：
5.8
作者：
Duncan, AM;Merz, BE;Kurzer, MS
通讯作者：
Kurzer, MS
影响因子：
3.9
作者：
Probst-Hensch, NM;Ingles, SA;Henderson, BE
通讯作者：
Henderson, BE