Identifiable reticulospinal neurons of the adult zebrafish, Brachydanio rerio
Identifiable reticulospinal neurons of the adult zebrafish, Brachydanio rerio
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成年斑马鱼（Brachydanio rerio）可识别的网状脊髓神经元
DOI：
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
R. C. Eaton
中科院分区：
文献类型：
--
作者：
Robert K. K. Lee;R. C. Eaton
斑马鱼幼鱼Brachydanio rerio的网状脊髓神经元已被分为27种不同类型（Kimmel等人：Journal of Comparative Neurology 205：112-127，1982; Metcalfe等人：Journal of Comparative Neurology 251：147-159，1986）。其中19个是双边的，可以单独识别。由于大脑结构的大量重塑（例如，细胞死亡和神经元结构的改变），我们询问这些细胞是否在成年斑马鱼中被保存，以及在个体发育过程中幼体的神经元形态在多大程度上被保存。在我们的分析中，我们研究了网状神经元从84脑逆行标记的脊髓与HRP。我们发现，所有的reticulospinal类型的幼虫保留在成人的形态没有相当大的变化。许多神经元，包括Mauthner细胞和它的两个系列同源物MiD 2cm和MiD 3cm，可以单独和明确地识别。此外，后期发育（三级）神经元的出现导致某些神经元类型的数量增加。虽然三级神经元通常与相邻细胞同构，但它们可以具有自己独特的形态，因此也可以单独识别。我们认为三级神经元的出现可能有助于延长胚胎的行为能力。此外，耳区相邻节段（第VIII神经进入水平）的形态重复可能代表功能基序的复制，可能涉及已知涉及Mauthner细胞的C型逃逸反应。
Reticulospinal neurons of the larval zebrafish Brachydanio rerio have been categorized into 27 different types (Kimmel et al.: Journal of Comparative Neurology 205:112–127, 1982; Metcalfe et al.: Journal of Comparative Neurology 251:147–159, 1986). Nineteen of these occur as bilateral pairs which are individually identifiable. Since considerable remolding of brain structures (e.g., cell death and modifications of neuronal architecture) occurs during development, we ask if these cells are preserved in the adult zebrafish and the extent to which neuronal morphology of the larva is conserved during ontogeny. In our analysis, we studied reticular neurons from 84 brains retrogradely labelled from the spinal cord with HRP. We show that all reticulospinal types of the larva are retained without considerable change in morphology in the adult. Many neurons, including the Mauthner cell and two of its serial homologues, MiD2cm and MiD3cm, can be individually and unambiguously identified. In addition, the appearance of later developing (tertiary) neurons leads to an increase in the numbers of some neuron types. Although tertiary neurons are often isomorphic with neighboring cells, they can have unique morphologies of their own and, therefore, are also individually identifiable. We suggest that the appearance of tertiary neurons may serve to extend the behavioural repertoire of the embryo. Moreover, morphological repetitions in adjacent segments of the otic region (level of VIIIth nerve entry) may represent the replication of a functional motif, perhaps involving the C‐type escape response which is known to involve the Mauthner cell.
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影响因子：
4.6
作者：
E. Hanneman;B. Trevarrow;W. K. Metcalfe;C. Kimmel;M. Westerfield
通讯作者：
E. Hanneman;B. Trevarrow;W. K. Metcalfe;C. Kimmel;M. Westerfield
影响因子：
2.7
作者：
GRUNWALD, DJ;KIMMEL, CB;STREISINGER, G
通讯作者：
STREISINGER, G
海胆胚胎中谱系特异性基因的表达。
DOI：
10.1101/sqb.1985.050.01.041
发表时间：
1985
期刊：
Cold Spring Harbor symposia on quantitative biology
影响因子：
--
作者：
Davidson,EH;Flytzanis,CN;Lee,JJ;Robinson,JJ;Rose3rd,SJ;Sucov,HM
通讯作者：
Sucov,HM
DOI：
10.1073/pnas.80.8.2390
发表时间：
1983-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
GOLDMAN, SA;NOTTEBOHM, F
通讯作者：
NOTTEBOHM, F