Evaluating quality of life in frailty: applicability and clinimetric properties of the SarQoL(®) questionnaire.
Evaluating quality of life in frailty: applicability and clinimetric properties of the SarQoL(®) questionnaire.
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DOI：
10.1002/jcsm.12687
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发表时间：
2021-04
期刊：
影响因子：
--
通讯作者：
Beaudart C
中科院分区：
文献类型：
--
作者：
Geerinck A;Locquet M;Bruyère O;Reginster JY;Beaudart C
SarQOL®调查问卷是专门为测量石棺减少症患者的生活质量而设计的。虚弱和骨质疏松症有重叠的区域，特别是肌肉力量较弱和步速较慢，这可能意味着SarQOL可以提供虚弱的生活质量的衡量标准。本研究的目的是使用Fry标准来评估SARQOL问卷在身体虚弱方面的临床测量特性。分析来自萨科普尼症和随年龄增长的身体损伤研究的数据。采用Fry标准和生活质量量表、简式36项问卷和EQ-5D问卷对患者的脆弱程度进行评估。分别用Kruskal-Wallis方差分析、内部一致性(Cronbach‘s Alpha)、结构效度(通过假设检验)、重测信度(用组内相关系数)、测量误差(计算测量标准误差和最小可检测变化)和反应性(通过假设检验和标准化反应均值)进行评估。总共有382名参与者参加了验证，117名参与者参加了响应性评估。他们的年龄中位数为73岁(69-79岁)，服用5(3-8)种药物，并有4(3-5)种合并症。女性(n=223；58.4%)比男性多，总共有172名(45%)健壮、167名(44%)体弱前和43名(11%)体弱的参与者。当健壮[0.001(64.35-85.90)]、衰弱[62.54(53.33-69.57)]和衰弱[49.99(40.45-56.06)]受试者之间观察到显著较低的总体生活质量评分时，辨别力被证实。六个SarQOL领域的表现类似，根据脆弱状态，得分明显较低，但领域7(恐惧)是个例外。内部一致性良好(α=0.866)。采用简明36项和EQ-5D验证了收敛结构和发散结构的效度。重测信度良好[组内相关系数r=0.918(0.834-0.961)]，测量标准误差为3.88，最小可检测变化量为10.76点。我们发现，当9个假设中的5个得到证实时，我们发现了中等的反应性，加上总体SALQOL评分的大效应(校正后的标准化反应平均值为−1.44)。SARQOL问卷具有足够的临床测量特性，可用于临床实践和试验中的虚弱患者，并可提供比目前使用的通用问卷更合适和更详细的数据。
The SarQoL® questionnaire was specifically designed to measure quality of life (QoL) in sarcopenia. Frailty and sarcopenia have areas of overlap, notably weak muscle strength and slow gait speed, which may mean that the SarQoL could provide a measure of QoL in frailty. This study aimed to evaluate the clinimetric properties of the SarQoL questionnaire in physical frailty using the Fried criteria. Analyses were carried out on data from the Sarcopenia and Physical impairment with advancing Age study. Frailty was assessed with the Fried criteria and QoL with the SarQoL, the Short‐Form 36‐Item, and the EuroQoL 5‐Dimension (EQ‐5D) questionnaires. We evaluated discriminative power (with the Kruskal–Wallis analysis of variance test), internal consistency (with Cronbach's alpha), construct validity (through hypotheses testing), test–retest reliability (with the intraclass correlation coefficient), measurement error (calculating standard error of measurement and smallest detectable change), and responsiveness (through hypotheses testing and standardized response mean). In total, 382 participants were included for the validation and 117 for the responsiveness evaluation. They had a median age of 73 (69–79) years, took 5 (3–8) drugs, and had 4 (3–5) co‐morbidities. There were more women (n = 223; 58.4%) than men and, in total, 172 (45%) robust, 167 (44%) pre‐frail, and 43 (11%) frail participants. Discriminative power was confirmed when significantly lower (P < 0.001) overall SarQoL scores, and thus also worse QoL, were observed between robust [77.1 (64.35–85.90)], pre‐frail [62.54 (53.33–69.57)], and frail [49.99 (40.45–56.06)] participants. Six of the SarQoL domains performed likewise, with significantly lower scores according to frailty status with Domain 7 (fears) being the exception. Internal consistency was good (α = 0.866). Convergent (using Short‐Form 36‐Item and EQ‐5D) and divergent construct validity (using EQ‐5D) was confirmed. Test–retest reliability was excellent [intraclass correlation coefficient = 0.918 (0.834–0.961)], with a standard error of measurement of 3.88 and a smallest detectable change of 10.76 points. We found moderate responsiveness when five of the nine hypotheses were confirmed, coupled with a large effect size for the overall SarQoL score (corrected standardized response mean of −1.44). The SarQoL questionnaire has adequate clinimetric properties for use with frail patients in clinical practice and trials and could provide data that are more appropriate and detailed than the generic questionnaires currently used.
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影响因子：
7.2
作者：
GUYATT, GH;EAGLE, DJ;TURPIE, I
通讯作者：
TURPIE, I
影响因子：
4.2
作者：
Locquet, Medea;Beaudart, Charlotte;Bruyere, Olivier
通讯作者：
Bruyere, Olivier
影响因子：
8.9
作者：
Beaudart, Charlotte;Biver, Emmanuel;Bruyere, Olivier
通讯作者：
Bruyere, Olivier
影响因子：
3.9
作者：
Konstantynowicz, Jerzy;Abramowicz, Pawel;Beaudart, Charlotte
通讯作者：
Beaudart, Charlotte
DOI：
10.1111/j.1532-5415.2012.04054.x
发表时间：
2012-08-01
影响因子：
6.3
作者：
Collard, Rose M.;Boter, Han;Voshaar, Richard C. Oude
通讯作者：
Voshaar, Richard C. Oude