The impact of heating, ventilation and air conditioning (HVAC) design features on the transmission of viruses, including the 2019 novel coronavirus (COVID-19): A systematic review of humidity.
The impact of heating, ventilation and air conditioning (HVAC) design features on the transmission of viruses, including the 2019 novel coronavirus (COVID-19): A systematic review of humidity.
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DOI：
10.1371/journal.pone.0275654
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
气溶胶途径是许多病毒传播的途径。同样，最近的证据已经确定SARS-CoV-2的气溶胶传播是重要的。因此，公共卫生官员和专业人员一直在寻找有关供暖、通风和空调（HVAC）功能作为减轻病毒传播（特别是冠状病毒）的作用的数据。使用国际标准，进行了系统性综述，以全面识别和综合研究湿度对冠状病毒和流感传播的影响。24项相关研究的结果表明：对于SARS-CoV-2，从中等（40-60%）到高（>60%）的相对湿度（RH）增加与病毒存活率降低相关;尽管SARS-CoV-2的结果似乎一致，但冠状病毒的行为并不完全相同;流感病毒从低RH（<40%）增加到中等RH与持续性、感染性、生存能力和存活率降低相关，然而，湿度从中到高对流感的影响并不一致;介质、温度和暴露时间与冠状病毒和流感结果的不一致性有关。适应湿度以减轻病毒传播是复杂的。当控制湿度作为HVAC功能时，从业人员应考虑病毒类型和温度。未来的研究在设计实验时还应考虑暴露时间、温度和介质的影响，同时还应努力实现更标准化的测试程序。临床试验注册：PROSPERO 2020 CRD 42020193968。
The aerosol route has been a pathway for transmission of many viruses. Similarly, recent evidence has determined aerosol transmission for SARS-CoV-2 to be significant. Consequently, public health officials and professionals have sought data regarding the role of Heating, Ventilation, and Air Conditioning (HVAC) features as a means to mitigate transmission of viruses, particularly coronaviruses. Using international standards, a systematic review was conducted to comprehensively identify and synthesize research examining the effect of humidity on transmission of coronaviruses and influenza. The results from 24 relevant studies showed that: increasing from mid (40–60%) to high (>60%) relative humidity (RH) for SARS-CoV-2 was associated with decreased virus survival; although SARS-CoV-2 results appear consistent, coronaviruses do not all behave the same; increasing from low (<40%) to mid RH for influenza was associated with decreased persistence, infectivity, viability, and survival, however effects of increased humidity from mid to high for influenza were not consistent; and medium, temperature, and exposure time were associated with inconsistency in results for both coronaviruses and influenza. Adapting humidity to mitigate virus transmission is complex. When controlling humidity as an HVAC feature, practitioners should take into account virus type and temperature. Future research should also consider the impact of exposure time, temperature, and medium when designing experiments, while also working towards more standardized testing procedures. Clinical trial registration: PROSPERO 2020 CRD42020193968.
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DOI：
10.1038/s41579-021-00535-6
发表时间：
2021-08
期刊：
Nature reviews. Microbiology
影响因子：
--
作者：
Leung NHL
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影响因子：
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影响因子：
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