Poor Walking Speed Is Associated With Higher Segment-Specific Arterial Stiffness in Older Adult Japanese Community Dwellers: A Cross-Sectional Study.
Poor Walking Speed Is Associated With Higher Segment-Specific Arterial Stiffness in Older Adult Japanese Community Dwellers: A Cross-Sectional Study.
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DOI：
10.3389/fphys.2020.587215
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发表时间：
2020
影响因子：
4
通讯作者：
Nishiwaki M
中科院分区：
文献类型：
--
作者：
Ogawa N;Nanayama Tanaka C;Ishido M;Nakamura T;Nishiwaki M
步行速度作为步态能力的指标之一，是老年人身体素质的重要组成部分。已经研究了步行速度与动脉僵硬度的关系，但是不好的步行速度是否与老年人更高的节段特异性动脉僵硬度相关尚不清楚。因此，我们的目的是研究老年社区居民的步行速度和节段性动脉僵硬度之间的关系。这项研究是一项横断面研究的492老年日本社区居民（年龄范围，65至96岁）。心-臂PWV（hbPWV）、臂-踝PWV（baPWV）、心-踝PWV（haPWV）和心-踝血管指数（CAVI）被用作动脉硬度指标。步行速度，力量，灵活性和认知功能也进行了评估。参与者根据步行速度分为低（慢），中（中）和高（快）三分位数。快速组的CAVI和baPWV显著低于慢速组。从慢到快观察到CAVI和baPWV的显著降低趋势以及haPWV的降低趋势，而hbPWV在三分位数之间没有显著差异，并且没有明显的趋势。将CAVI和PWV的动脉硬度指数和主要混杂因素（如年龄、性别、体重指数、血压、认知功能和每种身体素质）的多重共线性标准化后，结果仍具有显著性。因此，这些研究结果表明，在老年社区居民中，步行速度差与中央和下肢的较高节段特异性动脉僵硬度相关，但与上肢无关。
Walking speed as one index of gait ability is an important component of physical fitness among older adults. Walking speed-arterial stiffness relationships have been studied, but whether poor walking speed is associated with higher segment-specific arterial stiffness in older adults is unclear. We thus aimed to examine the relationship between walking speed and segmental arterial stiffness among older community dwellers. This study was a cross-sectional study of 492 older Japanese community dwellers (age range, 65 to 96 years). Heart-brachial PWV (hbPWV), brachial-ankle PWV (baPWV), heart-ankle PWV (haPWV), and cardio-ankle vascular index (CAVI) were used as arterial stiffness indices. Walking speed, strength, flexibility, and cognitive function were also assessed. The participants were categorized into low (Slow), middle (Middle), and high (Fast) tertiles according to walking speed. The CAVI and baPWV were significantly lower in Fast than in Slow. Significant decreasing trends in CAVI and baPWV and a tendency toward decreasing trend in haPWV were observed from Slow to Fast, whereas hbPWV did not significantly differ among tertiles and no trend was evident. The results remained significant after normalizing CAVI and PWVs for multicollinearity of arterial stiffness indices and major confounding factors, such as age, gender, body mass index, blood pressure, cognitive function, and each physical fitness. Therefore, these findings suggest that poor walking speed is associated with higher segment-specific arterial stiffness of the central and lower limbs, but not of upper, in older adult community dwellers.
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DOI：
10.1136/bmj.b4460
发表时间：
2009-11-10
期刊：
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影响因子：
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作者：
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