Molecular evolution of odorant-binding protein genes OS-E and OS-F in Drosophila.
Molecular evolution of odorant-binding protein genes OS-E and OS-F in Drosophila.
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果蝇中气味结合蛋白基因 OS-E 和 OS-F 的分子进化。
DOI:
10.1093/genetics/155.1.117
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发表时间:
2000
期刊:
影响因子:
3.3
通讯作者:
Carlson,JR
中科院分区:
文献类型:
--
作者:
Hekmat-Scafe,DS;Dorit,RL;Carlson,JR
The Drosophila olfactory genesOS-EandOS-Fare members of a family of genes that encode insect odorant-binding proteins (OBPs). OBPs are believed to transport hydrophobic odorants through the aqueous fluid within olfactory sensilla to the underlying receptor proteins. The recent discovery of a large family of olfactory receptor genes in Drosophila raises new questions about the function, diversity, regulation, and evolution of the OBP family. We have investigated theOS-EandOS-Fgenes in a variety of Drosophila species. These studies highlight potential regions of functional significance in the OS-E and OS-F proteins, which may include a region required for interaction with receptor proteins. Our results suggest that the two genes arose by an ancient gene duplication, and that in some lineages, one or the other gene has been lost. InD. virilis, theOS-Fgene shows a different spatial pattern of expression than inD. melanogaster.One of theOS-Fintrons shows a striking degree of conservation between the two species, and we identify a putative regulatory sequence within this intron. Finally, a phylogenetic analysis places both OS-E and OS-F within a large family of insect OBPs and OBP-like proteins.
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影响因子:
3.8
作者:
Paesen,GC;Happ,GM
通讯作者:
Happ,GM
影响因子:
10.7
作者:
C. Russo;N. Takezaki;M. Nei
通讯作者:
C. Russo;N. Takezaki;M. Nei
DOI:
--
发表时间:
1994
期刊:
影响因子:
--
作者:
D. Kodrík;V. Filippov;M. Filippova;F. Sehnal
通讯作者:
F. Sehnal
DOI:
10.1007/978-1-4615-1847-1_3
发表时间:
1995
期刊:
--
影响因子:
--
作者:
J. Powell;R. DeSalle
通讯作者:
J. Powell;R. DeSalle
影响因子:
3.3
作者:
Kim,MS;Repp,A;Smith,DP
通讯作者:
Smith,DP