A systematic review of the incidence and prevalence of autoimmune disease in multiple sclerosis.
A systematic review of the incidence and prevalence of autoimmune disease in multiple sclerosis.
复制标题
对多发性硬化症中自身免疫性疾病的发病率和患病率进行系统的综述。
DOI：
10.1177/1352458514564490
复制
发表时间：
2015-03
期刊：
影响因子：
--
通讯作者：
Trojano M
中科院分区：
文献类型：
--
作者：
Marrie RA;Reider N;Cohen J;Stuve O;Sorensen PS;Cutter G;Reingold SC;Trojano M
随着新疗法的出现，增加了自身免疫性疾病的风险，了解多发性硬化症（MS）中自身免疫性疾病的发病率越来越重要。本综述的目的是评估MS中共病自身免疫性疾病的发病率和患病率。检索了PUBMED、EMBASE、SCOPUS和Web of Knowledge数据库、会议记录和检索到的文章的参考文献列表，并由两位评审员独立筛选摘要。由一名审查员使用标准化数据收集表提取数据，并由第二名审查员验证结果。我们使用标准化方法评估纳入研究的质量，并对基于人群的研究进行荟萃分析。61篇文章符合纳入标准。我们观察到大量的异质性方面的人口研究，确定合并症的方法，并报告的结果。仅基于基于人群的研究，最常见的自身免疫性合并症是银屑病（7.74%）和甲状腺疾病（6.44%）。我们的研究结果还表明，炎症性肠病的风险增加，可能是葡萄膜炎和类天疱疮。在所确定的研究中，只有不到一半的研究是高质量的。需要在全世界的管辖范围内进行基于人口的研究，报告针对年龄、性别和族裔的发病率和流行率估计数。
As new therapies emerge which increase the risk of autoimmune disease it is increasingly important to understand the incidence of autoimmune disease in multiple sclerosis (MS). The purpose of this review is to estimate the incidence and prevalence of comorbid autoimmune disease in MS. The PUBMED, EMBASE, SCOPUS and Web of Knowledge databases, conference proceedings, and reference lists of retrieved articles were searched, and abstracts were independently screened by two reviewers. The data were abstracted by one reviewer using a standardized data collection form, and the findings were verified by a second reviewer. We assessed quality of the included studies using a standardized approach and conducted meta-analyses of population-based studies. Sixty-one articles met the inclusion criteria. We observed substantial heterogeneity with respect to the populations studied, methods of ascertaining comorbidity, and reporting of findings. Based solely on population-based studies, the most prevalent autoimmune comorbidities were psoriasis (7.74%) and thyroid disease (6.44%). Our findings also suggest an increased risk of inflammatory bowel disease, likely uveitis and possibly pemphigoid. Fewer than half of the studies identified were of high quality. Population-based studies that report age, sex and ethnicity-specific estimates of incidence and prevalence are needed in jurisdictions worldwide.
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DOI：
10.1111/j.1445-5994.1972.tb03071.x
发表时间：
1972-01-01
期刊：
AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE
影响因子：
--
作者：
BAKER, HWG;BALLA, JI;EBELING, P
通讯作者：
EBELING, P
影响因子：
1.9
作者：
Borhani-Haghighi, Afshin;Ansari, Neda;Lankarani, Kamran B.
通讯作者：
Lankarani, Kamran B.
影响因子：
9.9
作者：
de Seze, J;Devos, D;Vermersch, P
通讯作者：
Vermersch, P
影响因子：
2.7
作者：
Basiri, Keivan;Etemadifar, Masoud;Zarghami, Neda
通讯作者：
Zarghami, Neda
影响因子：
4.4
作者：
Durelli, L;Oggero, A;Faggiano, F
通讯作者：
Faggiano, F