Prevalence of metabolic syndrome in Bangladesh: a systematic review and meta-analysis of the studies.
Prevalence of metabolic syndrome in Bangladesh: a systematic review and meta-analysis of the studies.
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DOI：
10.1186/s12889-018-5209-z
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发表时间：
2018-03-02
影响因子：
4.5
通讯作者：
Turin TC
中科院分区：
文献类型：
--
作者：
Chowdhury MZI;Anik AM;Farhana Z;Bristi PD;Abu Al Mamun BM;Uddin MJ;Fatema J;Akter T;Tani TA;Rahman M;Turin TC
代谢综合征（MS）是一组健康问题，它为严重的健康状况奠定了基础，并使个人患心血管疾病、糖尿病和中风的风险更高。全球成年人群中多发性硬化症的患病率呈上升趋势，孟加拉国也不例外。根据一些流行病学研究，多发性硬化症在孟加拉国非常普遍，并且在过去的几十年里急剧增加。为了清楚地了解目前的情况，我们进行了系统回顾和荟萃分析，目的是利用科学文献中已发表的数据评估孟加拉国人群中代谢综合征的患病率。我们检索了MEDLINE、EMBASE和PubMed，并手动检查了所有确定的描述孟加拉国多发性硬化患病率的相关出版物的参考文献。随机效应荟萃分析用于汇总患病率。采用形式检验和亚组分析探讨异质性。研究质量和发表偏倚也进行了探讨。电子和灰色文献检索检索到491篇可能相关的论文。在剔除重复、审查题目和摘要以及筛选全文后，最终选择了10项研究。大多数研究是在农村人口中进行的，研究参与者大多是女性。不论性别和定义代谢综合征的标准，代谢综合征的加权合并患病率为30.0%，存在高度异质性。代谢综合征加权合并患病率女性（32%）高于男性（25%），但无统计学意义（p = 0.434）。当使用改良的NCEP ATP III标准来定义多发性硬化症时，患病率最高（37%），而当使用WHO标准时，患病率最低（20%）。在大多数情况下，地理区域（城市/农村）被确定为研究之间异质性的来源。大多数研究符合研究质量评价标准，但样本量标准不足，也有证据表明研究效应小。孟加拉国的代谢综合征患病率很高，而且还在上升。需要采取旨在初级预防的战略，以减缓发病率的进一步上升，并降低与代谢综合征有关的发病率和死亡率。本文的在线版本（10.1186/s12889-018-5209-z）包含补充内容，仅供授权用户使用。
Metabolic syndrome (MS) is a cluster of health problems that set the stage for serious health conditions and places individuals at higher risk of cardiovascular disease, diabetes and stroke. The worldwide prevalence of MS in the adult population is on the rise and Bangladesh is no exception. According to some epidemiological study, MS is highly prevalent in Bangladesh and has increased dramatically in last few decades. To provide a clear picture of the current situation, we conducted a systematic review and meta-analysis with an objective to assess the prevalence of metabolic syndrome among the Bangladeshi population using data already published in the scientific literature. We searched MEDLINE, EMBASE and PubMed and manually checked references of all identified relevant publications that described the prevalence of MS in Bangladesh. Random effects meta-analysis was used to pool the prevalence. Heterogeneity was explored using formal tests and subgroup analyses. Study quality and publication bias was also explored. Electronic and grey literature search retrieved 491 potentially relevant papers. After removing duplicates, reviewing titles and abstracts and screening full texts, 10 studies were finally selected. Most of the studies were conducted in rural populations and study participants were mostly females. The weighted pooled prevalence of metabolic syndrome regardless of gender and criteria used to define metabolic syndrome, was 30.0% with high heterogeneity observed. Weighted pooled prevalence of metabolic syndrome is higher in females (32%) compared to males (25%) though not statistically significant (p = 0.434). Prevalence was highest (37%) when Modified NCEP ATP III criteria was used to define MS, while it was lowest (20%) when WHO criteria was used. In most cases, geographical area (urban/rural) was identified as a source of heterogeneity between the studies. Most of the studies met study quality assessment criteria’s except adequate sample size criteria and evidence of small study effect was also detected. The prevalence of metabolic syndrome is high and rising in Bangladesh. Strategies aimed at primary prevention are required to mitigate a further increase in the prevalence and for the reduction of the morbidity and mortality associated with metabolic syndrome. The online version of this article (10.1186/s12889-018-5209-z) contains supplementary material, which is available to authorized users.
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2.6
作者：
Ahsan Karar Z;Alam N;Kim Streatfield P
通讯作者：
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通讯作者：
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作者：
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