Epidemiologic studies in agricultural populations: observations and future directions.
Epidemiologic studies in agricultural populations: observations and future directions.
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DOI：
10.1080/10599240902779436
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发表时间：
2009
影响因子：
2.4
通讯作者：
Freeman LB
中科院分区：
文献类型：
--
作者：
Blair A;Freeman LB
本文综述了农业人群中癌症的流行病学研究，以确定可能的关联，并为今后的调查提供重点。对农民死亡率调查的荟萃分析发现，包括结缔组织、非霍奇金淋巴瘤、霍奇金病、多发性骨髓瘤和皮肤癌、胃癌和脑癌在内的几种癌症的发病率过高，而总死亡率、心脏病、总癌症以及食道癌、结肠癌、肺癌和膀胱癌的发病率则有所下降。对个别癌症研究的荟萃分析也支持这些发现，表明有必要确定可能导致这种死亡模式的暴露和生活方式因素。尽管对可能与农民有共同农药接触的其他职业的癌症研究表明，与农民的观察结果有一些相似之处，但总体模式却大不相同。这表明农药不太可能完全解释在农民中观察到的癌症和其他疾病模式。由于暴露程度因农场经营类型而异，个体农民的暴露程度可能有很大差异。未来的研究需要集中在全范围的暴露，以充分了解农民的癌症模式。
This paper reviews epidemiologic studies of cancer among agricultural populations to identify possible associations and to provide a focus for future investigations. Meta-analyses of mortality surveys of farmers find excesses of several cancers, including connective tissue, non-Hodgkin lymphoma, Hodgkin disease, and multiple myeloma and cancers of the skin, stomach and brain and deficits for total mortality, heart disease, total cancer, and cancers of the esophagus, colon, lung and bladder. Meta-analyses of studies of individual cancers also support these findings indicating a need to identify exposures and lifestyle factors that might account for this mortality pattern. Although cancer studies of other occupations that might have pesticide exposures in common with farmers show some similarities with observations among farmers, the overall patterns are quite different. This suggests that pesticides are not likely to fully explain the cancer and other disease patterns observed among farmers. Because exposures vary by type of farm operation, exposures for individual farmers can differ considerably. Studies in the future need to focus on the full range of exposures to fully understand the cancer pattern in farmers.
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影响因子：
5.6
作者：
Blair, A;Sandler, DP;Alavanja, MCR
通讯作者：
Alavanja, MCR
影响因子：
4.9
作者：
Amre, DK;Infante-Rivard, C;Ernst, P
通讯作者：
Ernst, P
影响因子：
3.5
作者：
Mills, PK;Kwong, S
通讯作者：
Kwong, S
影响因子：
5
作者：
Mastrangelo, G;Grange, JM;Lange, JH
通讯作者：
Lange, JH
影响因子：
6.3
作者：
Khuder, SA;Schaub, EA;Keller-Byrne, JE
通讯作者：
Keller-Byrne, JE