The impact of periodontitis on vascular endothelial dysfunction.

The impact of periodontitis on vascular endothelial dysfunction.
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牙周炎对血管内皮功能障碍的影响

DOI:
10.3389/fcimb.2022.998313
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发表时间:
2022
影响因子:
5.7
通讯作者:
--
中科院分区:
医学2区
文献类型:
--
作者:

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牙周炎是一种口腔炎症性疾病,起源于牙周微生物区系失调,与宿主免疫炎症反应的失调有关。这种慢性感染不仅危害口腔健康,而且是各种血管疾病发生和发展的危险因素,如高血压、动脉粥样硬化和冠状动脉疾病。血管内皮细胞功能障碍是血管疾病的首要病理特征。阐明牙周炎与血管内皮功能障碍之间的关系,无疑是了解牙周炎与血管疾病之间潜在关系的关键突破。然而,目前缺乏对他们关系的最新审查。因此,在这篇综述中,我们主要关注牙周炎在血管内皮细胞功能障碍中的意义。
Periodontitis, an oral inflammatory disease, originates from periodontal microbiota dysbiosis which is associated with the dysregulation of host immunoinflammatory response. This chronic infection is not only harmful to oral health but is also a risk factor for the onset and progress of various vascular diseases, such as hypertension, atherosclerosis, and coronary arterial disease. Vascular endothelial dysfunction is the initial key pathological feature of vascular diseases. Clarifying the association between periodontitis and vascular endothelial dysfunction is undoubtedly a key breakthrough for understanding the potential relationship between periodontitis and vascular diseases. However, there is currently a lack of an updated review of their relationship. Therefore, we aim to focus on the implications of periodontitis in vascular endothelial dysfunction in this review.
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