Regional differences in the developmental trajectory of lateralization of the language network.
Regional differences in the developmental trajectory of lateralization of the language network.
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DOI：
10.1002/hbm.22179
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发表时间：
2014-01
影响因子：
4.8
通讯作者：
Gaillard, William Davis
中科院分区：
文献类型：
--
作者：
Berl, Madison M.;Mayo, Jessica;Parks, Erin N.;Rosenberger, Lisa R.;VanMeter, John;Ratner, Nan Bernstein;Vaidya, Chandan J.;Gaillard, William Davis
建立语言优势的时间和发展因素知之甚少。我们调查了4至12岁儿童（n=57）的分布式语言网络的传统额颞区和调节性额前-小脑区的偏侧化程度-这是语言巩固的关键时期。我们研究了语言偏侧化的强度和神经心理测量与任务绩效之间的关系。基本的语言网络是由四个与语言功能的不断成熟，证明了加强偏侧化在传统的额颞语言区域;颞区强烈和一贯偏侧化的7岁，而额叶区有较大的变异性，并不强烈偏侧化通过10岁。与此相反，调制前额叶小脑区域是最不强烈的偏侧化和偏侧化程度与年龄无关。更强的核心语言技能与小脑更大的右侧化显著相关。
The timing and developmental factors underlying the establishment of language dominance are poorly understood. We investigated the degree of lateralization of traditional fronto-temporal and modulatory prefrontal-cerebellar regions of the distributed language network in children (n=57) ages 4 to 12 – a critical period for language consolidation. We examined the relationship between the strength of language lateralization and neuropsychological measures and task performance. The fundamental language network is established by four with ongoing maturation of language functions as evidenced by strengthening of lateralization in the traditional frontotemporal language regions; temporal regions were strongly and consistently lateralized by seven, while frontal regions had greater variability and were less strongly lateralized through age ten. In contrast, the modulatory prefrontal-cerebellar regions were the least strongly lateralized and degree of lateralization was not associated with age. Stronger core language skills were significantly correlated with greater right lateralization in the cerebellum.
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影响因子：
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通讯作者：
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