Correlations between features of event-related potentials and Autism Spectrum Quotient scores
Correlations between features of event-related potentials and Autism Spectrum Quotient scores
复制标题
事件相关电位特征与自闭症谱商得分之间的相关性
DOI：
10.1016/j.jocn.2018.10.070
复制
发表时间：
2019
影响因子：
2
通讯作者：
Wang Ridey Hsiao
中科院分区：
文献类型：
--
作者：
Wang Gang;Kino Mai;Yamauchi Kei;Wang Ridey Hsiao
自闭症谱系障碍（ASD）是一种神经发育障碍，其特征是社会沟通和社会互动的缺陷。ASD包括从轻度到重度自闭症特征的连续表达。本研究的目的是探讨事件相关电位（ERP）在视听启动和自闭症谱系商（AQ）分数，其中包括5个不同领域的子分数之间的相关性：社会技能，注意转换，注意细节，沟通和想象。高密度脑电图记录，而参与者进行了视觉-听觉启动任务，需要分类的听觉刺激后，语义一致或不一致的视觉引物。听觉目标语义一致和不一致的引物后的ERPs的差异发生在200 ms和600 ms之间的后颞电极。P7时与不一致听觉刺激相关的振幅与整体AQ评分呈负相关，与沟通分项评分呈正相关。与一致性刺激相关的振幅与注意细节分项分数呈正相关。此外，PO 7振幅与沟通分项评分呈负相关。结果表明，跨通道启动的电生理特征与AQ成绩之间存在显著的相关性。我们的研究结果表明，电生理参数可能是有用的工具，以评估自闭症特质表达的严重程度。
Autism spectrum disorder (ASD) is a neurodevelopmental disorder and is characterized by deficits in social communication and social interaction. ASD includes a continuum from mild to severe expression of autistic traits. The purpose of the present study was to investigate correlations between event-related potentials (ERPs) during visual-auditory priming, and Autism Spectrum Quotient (AQ) scores, which include subscores in 5 different areas: social skills, attention switching, attention to detail, communication, and imagination. High-density electroencephalograms were recorded while participants performed a visual-auditory priming task that required categorization of auditory stimuli presented following a semantically congruent or incongruent visual primer. Differences in ERPs to auditory targets following semantically congruent and incongruent primers occurred between 200 ms and 600 ms at the posterior temporal electrodes. Amplitudes associated with incongruent auditory stimuli at P7 were negatively correlated with overall AQ scores, and positively correlated with communication subscores. Amplitudes associated with congruent stimuli were positively correlated with attention to detail subscores. In addition, PO7 amplitudes were negatively correlated with communication subscores. The results demonstrate significant correlations between electrophysiological features of cross-modal priming and AQ scores. Our findings suggest that electrophysiological parameters may be useful tools to evaluate the severity of autistic trait expression.
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DOI：
10.1016/s0926-6410(02)00066-6
发表时间：
2002-06-01
期刊：
COGNITIVE BRAIN RESEARCH
影响因子：
--
作者：
Molholm, S;Ritter, W;Foxe, JJ
通讯作者：
Foxe, JJ
自闭症心理理论。
DOI：
--
发表时间：
2008
期刊：
影响因子：
--
作者：
S. Baron
通讯作者：
S. Baron
自闭症和阿斯伯格综合症。
影响因子：
3.6
作者：
K. Towbin
通讯作者：
K. Towbin
DOI：
10.1111/j.1469-7610.2007.01766.x
发表时间：
2007-08-01
影响因子：
7.6
作者：
Smith, Elizabeth G.;Bennetto, Loisa
通讯作者：
Bennetto, Loisa
影响因子：
5.7
作者：
Hertz, Uri;Amedi, Amir
通讯作者：
Amedi, Amir