Specific association of lectin LecB with the surface of Pseudomonas aeruginosa: role of outer membrane protein OprF.
Specific association of lectin LecB with the surface of Pseudomonas aeruginosa: role of outer membrane protein OprF.
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DOI:
10.1371/journal.pone.0046857
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Jaeger KE
中科院分区:
文献类型:
--
作者:
Funken H;Bartels KM;Wilhelm S;Brocker M;Bott M;Bains M;Hancock RE;Rosenau F;Jaeger KE
The fucose binding lectin LecB affects biofilm formation and is involved in pathogenicity of Pseudomonas aeruginosa. LecB resides in the outer membrane and can be released specifically by treatment of an outer membrane fraction with fucose suggesting that it binds to specific ligands. Here, we report that LecB binds to the outer membrane protein OprF. In an OprF-deficient P. aeruginosa mutant, LecB is no longer detectable in the membrane but instead in the culture supernatant indicating a specific interaction between LecB and OprF.
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DOI:
10.1111/j.1574-695x.2000.tb01505.x
发表时间:
2000-09-01
影响因子:
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作者:
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通讯作者:
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通讯作者:
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