Adolescent blood pressure, body mass index and skin folds: sorting out the effects of early weight and length gains.
Adolescent blood pressure, body mass index and skin folds: sorting out the effects of early weight and length gains.
复制标题
DOI：
10.1136/jech.2010.124842
复制
发表时间：
2012-02
影响因子：
6.3
通讯作者：
Victora CG
中科院分区：
文献类型：
--
作者：
Menezes AM;Hallal PC;Dumith SC;Matijasevich AM;Araújo CL;Yudkin J;Osmond C;Barros FC;Victora CG
虽然长期以来有证据表明，促进低收入环境中幼儿快速成长的短期效益，但最近的研究表明，早期体重增加也会增加成年人患慢性病的风险。本文试图分离早期生活体重和长度/身高增加对血压，身体质量指数（BMI），皮肤褶皱总和和肩胛下/三头肌皮肤褶皱比率在14-15岁的影响。 样本包括来自巴西的一个前瞻性的基于人口的出生队列的833名成员。条件尺寸（体重或身高）分析用于表示在给定年龄下观察到的尺寸与基于回归的预期尺寸之间的差异，包括相同人体测量指数的所有先前测量。一个积极的条件重量或高度表明增长速度比预期给定的先前大小。所有年龄范围的条件体重与大多数结局呈正相关;在调整条件长度/高度后，4岁时条件体重的每个z评分与青春期皮肤褶皱总和增加6.1 mm（95% CI 4.5至7.6）相关。 结果与条件长度/高度的关联大多为负或不显著-在调整条件重量后，每个z评分与皮肤褶皱总和减少2.4 mm（95% CI-3.8至1.1）相关。 未发现与皮肤褶皱比率相关。促进快速的身高/身高增加而不过度增加体重似乎对长期结果有益，但这需要其他研究的证实。
Although there is longstanding evidence of the short-term benefits of promoting rapid growth for young children in low-income settings, more recent studies suggest that early weight gain can also increase the risk of chronic diseases in adults. This paper attempts to separate the effects of early life weight and length/height gains on blood pressure, body mass index (BMI), sum of skin folds and subscapular/triceps skin fold ratio at 14–15 years of age. The sample comprised 833 members of a prospective population-based birth cohort from Brazil. Conditional size (weight or height) analyses were used to express the difference between observed size at a given age and expected size based on a regression, including all previous measures of the same anthropometric index. A positive conditional weight or height indicates growing faster than expected given prior size. Conditional weights at all age ranges were positively associated with most outcomes; each z-score of conditional weight at 4 years was associated with an increase of 6.1 mm in the sum of skin folds (95% CI 4.5 to 7.6) in adolescence after adjustment for conditional length/height. Associations of the outcomes with conditional length/height were mostly negative or non-significant—each z-score was associated with a reduction of 2.4 mm (95% CI −3.8 to −1.1) in the sum of skin folds after adjustment for conditional weight. No associations were found with the skin fold ratio. The promotion of rapid length/height gain without excessive weight gain seems to be beneficial for long-term outcomes, but this requires confirmation from other studies.
登录
查看更多内容
影响因子：
7.2
作者：
KANNEL, WB;CUPPLES, LA;HIGGINS, M
通讯作者：
HIGGINS, M
影响因子：
2.5
作者：
Martorell, Reynaldo;Ho, Teresa J.
通讯作者：
Ho, Teresa J.
影响因子：
37.8
作者：
Law, CM;Shiell, AW;de Swiet, M
通讯作者：
de Swiet, M
DOI：
10.3945/ajcn.2008.27139
发表时间：
2009-05
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Adair LS;Martorell R;Stein AD;Hallal PC;Sachdev HS;Prabhakaran D;Wills AK;Norris SA;Dahly DL;Lee NR;Victora CG
通讯作者：
Victora CG
影响因子：
7.1
作者：
Stettler, N;Kumanyika, SK;Stallings, VA
通讯作者：
Stallings, VA