Comparison of quiescent inflow single-shot and native space for nonenhanced peripheral MR angiography.

Comparison of quiescent inflow single-shot and native space for nonenhanced peripheral MR angiography.
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DOI:
10.1002/jmri.24124
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发表时间:
2013-12
影响因子:
4.4
通讯作者:
Edelman, Robert R.
Edelman, Robert R.
中科院分区:
医学2区
文献类型:
--
作者:
Ward, Emily V.;Galizia, Mauricio S.;Usman, Asad;Popescu, Andrada R.;Dunkle, Eugene;Edelman, Robert R.

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To evaluate two nonenhanced MRA methods: quiescent-interval single-shot (QISS) and Native SPACE (NATIVE= Non-contrast Angiography of the Arteries and Veins; SPACE = Sampling Perfection with Application Optimized Contrast by using different flip angle Evolution), using contrast-enhanced MR angiography (CEMRA) as a reference standard. 20 patients (14 male, mean 69.3 years old) referred for lower extremity MRA were recruited in a HIPAA-compliant prospective study. QISS and Native SPACE of the lower extremities were performed at 1.5T with a hybrid dual-injection contrast-enhanced MRA as reference. Image quality and stenosis severity were assessed in segments by two blinded radiologists. Methods were compared with logistic regression for correlated data for diagnostic accuracy. Of 496 arterial segments, 24 were considered non-diagnostic on the Native SPACE images. There were no QISS or CEMRA imaging segments considered to be non-diagnostic. Image quality was significantly higher for QISS than for Native SPACE. QISS stenosis sensitivity (84.9%) was not significantly different from Native SPACE (87.3%). QISS had better specificity (95.6%) than Native SPACE (87.0%), p=0.0041. In comparison with QISS, Native SPACE proved less robust for imaging of the abdominal and pelvic segments. Native SPACE and QISS were sensitive for hemodynamically significant stenosis in this pilot study. QISS NEMRA demonstrated superior specificity and image quality, and was more robust in the abdominal and pelvic regions.
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