A conserved supergene locus controls colour pattern diversity in Heliconius butterflies.
A conserved supergene locus controls colour pattern diversity in Heliconius butterflies.
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DOI：
10.1371/journal.pbio.0040303
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发表时间：
2006-10
期刊：
影响因子：
9.8
通讯作者：
Jiggins CD
中科院分区：
文献类型：
--
作者：
Joron M;Papa R;Beltrán M;Chamberlain N;Mavárez J;Baxter S;Abanto M;Bermingham E;Humphray SJ;Rogers J;Beasley H;Barlow K;ffrench-Constant RH;Mallet J;McMillan WO;Jiggins CD
我们研究了相似的发育遗传机制是否参与了趋同进化和趋异进化。拟态昆虫以其多样的模式和显著的进化趋同性而闻名，它们在适应性进化中选择和限制各自作用的争论中发挥了重要作用。在这里，我们对比了三种蝴蝶，它们都是穆勒拟态的经典例子。我们使用的遗传连锁图显示，一个基因座，Yb，它控制的存在下，黄色带的地理小种的Heliconius melpomene，精确地映射到相同的位置，作为基因座铬，它有非常相似的表型效应，在其共同模仿H。埃拉托。此外，相同的基因组位置作为一个“超基因”，决定了第三个物种，H。沼田H. numata是一种具有非常不同的表型外观的物种，其许多形式模仿Melinaea属中不同的不相关的ithomiine蝴蝶。其他未连锁的颜色模式基因座映射到共模拟物H中的同源连锁群。melpomene和H. erato，但它们不参与H.沼田因此，来自H. melpomene和H. erato似乎已经控制了H的整个翼型变化。numata，大概是由于选择模拟“超基因”多态性没有中间体。虽然我们不能在这个阶段确认的同源性的基因座分离的三个物种，我们的研究结果意味着，一个保守的，但相对不受约束的机制模式切换可以影响模仿在根本上不同的方式。我们还表明，适应性进化，收敛和多样化，可以发生相同的基因组区域的重复参与。在适应性进化的一个有趣的例子中，遗传连锁分析确定了一个保守的区域，在远亲Heliconius蝴蝶物种中，它控制着翅膀图案和模仿的不同效果。
We studied whether similar developmental genetic mechanisms are involved in both convergent and divergent evolution. Mimetic insects are known for their diversity of patterns as well as their remarkable evolutionary convergence, and they have played an important role in controversies over the respective roles of selection and constraints in adaptive evolution. Here we contrast three butterfly species, all classic examples of Müllerian mimicry. We used a genetic linkage map to show that a locus, Yb, which controls the presence of a yellow band in geographic races of Heliconius melpomene, maps precisely to the same location as the locus Cr, which has very similar phenotypic effects in its co-mimic H. erato. Furthermore, the same genomic location acts as a “supergene”, determining multiple sympatric morphs in a third species, H. numata. H. numata is a species with a very different phenotypic appearance, whose many forms mimic different unrelated ithomiine butterflies in the genus Melinaea. Other unlinked colour pattern loci map to a homologous linkage group in the co-mimics H. melpomene and H. erato, but they are not involved in mimetic polymorphism in H. numata. Hence, a single region from the multilocus colour pattern architecture of H. melpomene and H. erato appears to have gained control of the entire wing-pattern variability in H. numata, presumably as a result of selection for mimetic “supergene” polymorphism without intermediates. Although we cannot at this stage confirm the homology of the loci segregating in the three species, our results imply that a conserved yet relatively unconstrained mechanism underlying pattern switching can affect mimicry in radically different ways. We also show that adaptive evolution, both convergent and diversifying, can occur by the repeated involvement of the same genomic regions. In an intriguing example of adaptive evolution, genetic linkage analysis identifies a conserved region in distantly relatedHeliconius butterfly species that controls the diverse effects of wing patterning and mimicry.
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影响因子：
3.3
作者：
CLARKE, CA;SHEPPARD, PM
通讯作者：
SHEPPARD, PM
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