The Use of DNA Probes in Dental Diagnosis and Therapy

The Use of DNA Probes in Dental Diagnosis and Therapy
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DNA 探针在牙科诊断和治疗中的应用

DOI:
10.1177/08959374870010012201
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发表时间:
1987
影响因子:
--
通讯作者:
R. Quivey
R. Quivey
中科院分区:
--
文献类型:
--
作者:
R. Quivey

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重组DNA技术现在允许开发针对越来越多的病原学疾病因子的遗传探针,包括那些在口腔环境中被怀疑的病原体。DNA探针方法和灵敏度的日益完善最终将允许它们在临床样品中普遍使用,以快速鉴定其细菌组成。探针技术的使用可能提供一种更容易、更准确、更节省时间的机制,用于鉴定来自口腔的挑剔微生物,其中许多微生物是费力和难以培养的。
Recombinant DNA technology now allows for the development of genetic probes specific for a growing number of etiologic disease agents, including those suspected pathogens in the oral environment. The increasing refinement of DNA probe methodologies and sensitivities will ultimately permit their commonplace use with clinical samples for the rapid identification of their bacterial compositions. The use of probe technology potentially offers a much more facile, accurate, and less time-consuming mechanism for the identification of fastidious micro-organisms from the oral cavity, many of which are laborious and difficult to cultivate.
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