Amphibian gut microbiota shifts differentially in community structure but converges on habitat-specific predicted functions.
Amphibian gut microbiota shifts differentially in community structure but converges on habitat-specific predicted functions.
复制标题
DOI：
10.1038/ncomms13699
复制
发表时间：
2016-12-15
影响因子：
16.6
通讯作者：
中科院分区：
文献类型：
--
作者：
复杂的微生物群落栖息在脊椎动物的消化系统中，但对自然栖息地中宿主相关微生物群的生态动态和功能的透彻理解是有限的。我们通过对生活在两个不同栖息地（池塘和溪流）的蝾螈幼虫进行实地调查和相互转移实验，研究了自然条件下环境条件在塑造肠道和皮肤微生物群中的作用。我们发现肠道和皮肤微生物群是生境特异性的，表明环境因素介导了群落结构。互惠转移表明，肠道微生物群对环境变化的反应不同，而皮肤微生物群则不同。溪流到池塘的幼虫将其肠道微生物群转变为池塘到池塘的幼虫，而池塘到溪流的幼虫则改变为不同于栖息地控制的群落结构。然而，在这两种情况下，预测的功能与目的地栖息地的幼虫相匹配。因此，微生物功能可以在没有分类一致性的情况下匹配，肠道微生物群似乎表现出宏基因组的可塑性。当宿主改变位置时，宿主相关微生物群落的结构或功能会发生变化。Bletz等人在池塘和溪流栖息地之间相互转移蝾螈幼虫，表明当宿主遇到新环境时，肠道微生物组在功能上发生了变化，但不一定是分类身份。
Complex microbial communities inhabit vertebrate digestive systems but thorough understanding of the ecological dynamics and functions of host-associated microbiota within natural habitats is limited. We investigate the role of environmental conditions in shaping gut and skin microbiota under natural conditions by performing a field survey and reciprocal transfer experiments with salamander larvae inhabiting two distinct habitats (ponds and streams). We show that gut and skin microbiota are habitat-specific, demonstrating environmental factors mediate community structure. Reciprocal transfer reveals that gut microbiota, but not skin microbiota, responds differentially to environmental change. Stream-to-pond larvae shift their gut microbiota to that of pond-to-pond larvae, whereas pond-to-stream larvae change to a community structure distinct from both habitat controls. Predicted functions, however, match that of larvae from the destination habitats in both cases. Thus, microbial function can be matched without taxonomic coherence and gut microbiota appears to exhibit metagenomic plasticity. Host-associated microbial communities can shift in structure or function when hosts change locations. Bletz et al. reciprocally transfer salamander larvae between pond and stream habitats to show that gut microbiomes shift in function, but not necessarily taxonomic identities, when hosts encounter a new environment.
登录
查看更多内容
影响因子：
5.2
作者：
Comte J;Fauteux L;Del Giorgio PA
通讯作者：
Del Giorgio PA
影响因子：
4.2
作者：
Chang CW;Huang BH;Lin SM;Huang CL;Liao PC
通讯作者：
Liao PC
DOI：
10.1126/science.1224203
发表时间：
2012-06-08
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Costello EK;Stagaman K;Dethlefsen L;Bohannan BJ;Relman DA
通讯作者：
Relman DA
影响因子：
64.5
作者：
Chung H;Pamp SJ;Hill JA;Surana NK;Edelman SM;Troy EB;Reading NC;Villablanca EJ;Wang S;Mora JR;Umesaki Y;Mathis D;Benoist C;Relman DA;Kasper DL
通讯作者：
Kasper DL
DOI：
10.1073/pnas.1000080107
发表时间：
2011-03-15
影响因子：
11.1
作者：
Caporaso, J. Gregory;Lauber, Christian L.;Knight, Rob
通讯作者：
Knight, Rob