The modified NCEP ATP III criteria maybe better than the IDF criteria in diagnosing Metabolic Syndrome among Malays in Kuala Lumpur.
The modified NCEP ATP III criteria maybe better than the IDF criteria in diagnosing Metabolic Syndrome among Malays in Kuala Lumpur.
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DOI：
10.1186/1471-2458-10-678
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发表时间：
2010-11-06
影响因子：
4.5
通讯作者：
Bulgiba A
中科院分区：
文献类型：
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作者：
Moy FM;Bulgiba A
代谢综合征与2型糖尿病和心血管疾病的风险增加有关。然而，不同的专家组推荐了不同的诊断标准。在马来西亚，缺乏对这些不同诊断标准进行比较的研究。因此，我们的目的是在吉隆坡的一个马来队列中研究IDF和修改后的NCEP ATP III代谢综合征定义之间的一致性；并证明是否所有参与者都有相同的心脏代谢风险。这是一项分析性的横断面研究。获得了伦理方面的批准，所有参与者都表示知情同意。按标准方案进行人体测量、血压、空腹血糖和血脂测定。使用修改后的NCEP和IDF标准，分别有41.4%和38.2%的受试者诊断出代谢综合征。在改良的NCEP诊断为代谢综合征的患者中，有7.6%的患者被IDF标准遗漏。与采用这两种标准诊断的患者相比，按NCEP标准诊断的参与者的BMI和腰围较低，但心脏代谢风险较高。血压、血糖、总胆固醇和甘油三酯的不良反应比IDF组严重。这表明中心性肥胖可能不是这个马来人队列中心脏代谢风险增加的先决条件。代谢综合征在这个马来人队列中很常见，无论使用什么标准。修改后的NCEP-ATPIII标准可能更适合于这个马来队列的代谢综合征的诊断。
Metabolic Syndrome is associated with increased risk for type 2 diabetes and cardiovascular diseases. However, different diagnostic criteria have been recommended by different expert groups. In Malaysia, there is a lack of research comparing these different diagnostic criteria. Therefore, it is our aim to study the concordance between the IDF and the modified NCEP ATP III definitions of Metabolic Syndrome among a Malay cohort in Kuala Lumpur; and to demonstrate if all participants have the same cardiometabolic risks. This was an analytical cross sectional study. Ethics approval was obtained and informed consent was given by all participants. Anthropometric measurements, blood pressure, fasting blood glucose and lipid profile were taken following standard protocols. Metabolic Syndrome was diagnosed in 41.4% and 38.2% participants using the modified NCEP and IDF criteria respectively. Among those diagnosed with Metabolic Syndrome by modified NCEP, 7.6% were missed by the IDF criteria. Participants diagnosed by the modified NCEP criteria had lower BMI and waist circumference but had higher cardiometabolic risks than those diagnosed with both criteria. Their blood pressure, glucose, total cholesterol and triglyceride were more adverse than the IDF group. This demonstrated that central obesity may not be a prerequisite for the development of increased cardiometabolic risks within this Malay cohort. Metabolic syndrome is common in this Malay cohort regardless of the criterion used. The modified NCEP ATP III criteria may be more suitable in diagnosis of metabolic syndrome for this Malay cohort.
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影响因子：
4.9
作者：
Yoon, Y. S.;Lee, E. S.;Oh, S. W.
通讯作者：
Oh, S. W.
影响因子：
16.2
作者：
Lee, Jeannette;Ma, Stefan;Tai, E-Shyong
通讯作者：
Tai, E-Shyong
影响因子：
37.8
作者：
Alberti, K. G. M. M.;Eckel, Robert H.;Smith, Sidney C., Jr.
通讯作者：
Smith, Sidney C., Jr.
影响因子：
16.2
作者：
Tan, CE;Ma, S;Tai, ES
通讯作者：
Tai, ES
影响因子：
5.1
作者：
通讯作者：
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