Event-Related Potential Studies of Cognitive Processing Abnormalities in Autism

Event-Related Potential Studies of Cognitive Processing Abnormalities in Autism
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自闭症认知处理异常的事件相关电位研究

DOI:
10.1007/978-1-4614-6843-1_4
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发表时间:
2013
期刊:
L'Encephale
影响因子:
--
通讯作者:
M. Casanova
M. Casanova
中科院分区:
--
文献类型:
--
作者:
E. Sokhadze;Joshua M. Baruth;A. Tasman;M. Casanova

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自闭症被认为是一种普遍的发育障碍(PDD),通常在生命的前3年很明显(Ruble and Brown 2003; Volkmar and paul 2003)。已经提出了几种神经心理学模型来解释自闭症谱系障碍(ASD)中发现的认知缺陷(Baron-Cohen 2004),其中一种是基于执行功能的显著缺陷(Burack 1994; Hughes et al. 1994; Ozonoff 1997; Hill 2004)。执行功能技能属于那些前额叶功能的范围,这些功能在目标导向行为的实施中促进解决问题、灵活的设置转换和前瞻性计划(Hughes et al. 1994)。这种自闭症模型中的执行缺陷与特定的额叶机制有关,主要与前额叶和中额叶皮层以及相关的神经回路有关(Bishop 1993; Hill 2004)。执行功能领域对发展性精神病理学具有重要意义,但对于自闭症症状和体征的因果解释是否完全源于额叶执行功能异常,仍然存在疑问(Griffith et al. 1999)。
Autism is recognized as a pervasive developmental disorder (PDD) usually evident during the first 3 years of life (Ruble and Brown 2003; Volkmar and Pauls 2003). Several neuropsychological models have been proposed to explain the cognitive deficits found in autism spectrum disorders (ASD) (Baron-Cohen 2004), one of which is based on salient deficits in executive function (Burack 1994; Hughes et al. 1994; Ozonoff 1997; Hill 2004). Executive functioning skills fall under the purview of those prefrontal functions that facilitate problem-solving, flexible set-shifting, and forward planning in the implementation of goal-directed behavior (Hughes et al. 1994). The executive deficits in this autism model have been related to specific frontal mechanisms, principally to the prefrontal and midfrontal cortices and associated neural circuitries (Bishop 1993; Hill 2004). The domain of executive functions has significant implications for developmental psychopathologies, but there are still doubts (Griffith et al. 1999) regarding the causal explanation of signs and symptoms in autism as stemming exclusively from frontal executive functioning abnormalities.
DOI: --
发表时间: --
期刊: --
影响因子: --
作者:
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DOI: 10.1111/1469-8986.3510023
发表时间: 1998-01-01
期刊: PSYCHOPHYSIOLOGY
影响因子: 3.7
作者:
Katayama, J;Polich, J
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DOI: 10.1080/10874208.2010.501500
发表时间: 2010-07-01
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DOI: 10.1093/cercor/4.4.428
发表时间: 1994-07-01
期刊: CEREBRAL CORTEX
影响因子: 3.7
作者:
FAVOROV, OV;KELLY, DG
通讯作者: KELLY, DG