Maternal lifestyle characteristics during pregnancy, and the risk of obesity in the offspring: a study of 5,125 children.

Maternal lifestyle characteristics during pregnancy, and the risk of obesity in the offspring: a study of 5,125 children.
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母亲怀孕期间的生活方式特征以及后代肥胖的风险:一项针对 5,125 名儿童的研究。

DOI:
10.1186/s12884-015-0498-z
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发表时间:
2015-03-21
影响因子:
3.1
通讯作者:
Sidossis LS
Sidossis LS
中科院分区:
医学3区
文献类型:
--
作者:
Mourtakos SP;Tambalis KD;Panagiotakos DB;Antonogeorgos G;Arnaoutis G;Karteroliotis K;Sidossis LS

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调查孕期体重增加、母亲年龄、孕期生活习惯(如体力活动、吸烟和饮酒)与8岁子代体重指数之间的关系。Α从国家数据库中随机抽取了5125名儿童的样本,并与他们的母亲进行了匹配。通过使用标准化问卷,进行了电话访谈,以收集诸如产妇怀孕年龄、妊娠期体重增加(GWG)、运动水平、吸烟和饮酒等信息。根据从国家数据库检索的数据(如身高和体重)计算后代8岁时的身体质量指数(BMI)状况。与久坐相比,8岁时每千克GWG超重/肥胖、吸烟和孕期轻度运动的几率分别为1.01(95%可信区间:1.00,1.02)、1.23(95%可信区间:1.03,1.47)和0.77(95%可信区间:0.65,0.91)。进一步分析显示,与GWG在推荐范围内的女性的后代相比,超过医学研究所(IOM)母亲体重增加建议的女性后代肥胖风险增加(OR: 1.45; 95%CI, 1.26, 1.67)。产妇年龄和饮酒与结果无关(p < 0.05)。怀孕期间的GWG、身体活动和吸烟状况与后代8岁时的肥胖显著相关。卫生保健专业人员应强烈建议妇女不要吸烟,并在怀孕期间进行适度运动,以防止后代在以后的生活中肥胖。
To investigate the association between gestational weight gain, maternal age and lifestyle habits (e.g., physical activity, smoking, and alcohol consumption) during pregnancy, with Body Mass Index of the offspring at the age of 8. Α random sample of 5,125 children was extracted from a national database and matched with their mothers. With the use of a standardised questionnaire, telephone interviews were carried out for the collection of information like: maternal age at pregnancy, gestational weight gain (GWG), exercise levels, smoking and alcohol consumption. The Body Mass Index (BMI) status of the offspring at the age of 8 was calculated from data retrieved from the national database (e.g., height and weight). The odds for being overweight/obese at the age of 8 for 1 kg GWG, for smoking, and for mild exercise during pregnancy compared to sedentary was 1.01 (95%CI: 1.00, 1.02), 1.23 (95%CI: 1.03, 1.47) and 0.77 (95%CI: 0.65, 0.91), respectively. Further analysis revealed that offspring of women who exceeded the Institute of Medicine (IOM) maternal weight gain recommendations were at an increased risk of obesity (OR: 1.45; 95%CI, 1.26, 1.67) compared with offspring of women with GWG within the recommended range. Maternal age and alcohol consumption were not associated with the outcome (p > 0.05). GWG, physical activity and smoking status during pregnancy were significantly associated with obesity for the offspring at the age of 8. Health care professionals should strongly advise women to not smoke and to perform moderate exercise during pregnancy to prevent obesity in the offspring in later life.
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