Annelid functional genomics reveal the origins of bilaterian life cycles.
Annelid functional genomics reveal the origins of bilaterian life cycles.
复制标题
DOI：
10.1038/s41586-022-05636-7
复制
发表时间：
2023-03
期刊：
影响因子：
64.8
通讯作者：
Martin-Duran, Jose M.
中科院分区：
文献类型：
--
作者：
Martin-Zamora, Francisco M.;Liang, Yan;Guynes, Kero;Carrillo-Baltodano, Allan M.;Davies, Billie E.;Donnellan, Rory D.;Tan, Yongkai;Moggioli, Giacomo;Seudre, Oceane;Tran, Martin;Mortimer, Kate;Luscombe, Nicholas M.;Hejnol, Andreas;Marletaz, Ferdinand;Martin-Duran, Jose M.
中间幼虫的间接发育存在于所有主要的动物谱系中，这使得幼虫在动物进化的大多数情况下都是中心。然而，幼虫是如何进化的仍然存在争议。在这里，我们表明，时间上的变化（即，heterochronies）在树干形成的基础上的多样化的幼虫和bilaterian生命周期。我们进行了染色体规模的基因组测序环节动物梭形欧文氏与转录组和表观基因组分析在生命周期中的这和其他两个环节动物。结果表明，梭形刺蛾取食幼虫的躯干发育推迟到变态前阶段，而大刺蛾无取食幼虫的躯干发育则在原肠胚形成后开始，逐渐变态，而旋丝双头蚤的躯干发育则在直接发育的胚胎中开始。因此，梭形棘球绦虫的胚胎首先发育成一个扩大的前部区域，形成幼虫组织和成虫头部。值得注意的是，这也发生在所谓的“头幼虫”的其他bilaterians，其中O. fusiformis幼虫显示出广泛的转录相似性。总之，我们的研究结果表明，时间解耦的头部和躯干的形成，最大限度地观察到头部幼虫，促进幼虫的进化Bilateria。这偏离了普遍的情况下，提出要么共同选择或创新的基因调控方案，以解释幼虫和成虫的起源。比较染色体规模的基因组测序和转录组和表观基因组分析三个不同种类的环节动物提供洞察幼虫的进化起源。
Indirect development with an intermediate larva exists in all major animal lineages, which makes larvae central to most scenarios of animal evolution. Yet how larvae evolved remains disputed. Here we show that temporal shifts (that is, heterochronies) in trunk formation underpin the diversification of larvae and bilaterian life cycles. We performed chromosome-scale genome sequencing in the annelid Owenia fusiformis with transcriptomic and epigenomic profiling during the life cycles of this and two other annelids. We found that trunk development is deferred to pre-metamorphic stages in the feeding larva of O. fusiformis but starts after gastrulation in the non-feeding larva with gradual metamorphosis of Capitella teleta and the direct developing embryo of Dimorphilus gyrociliatus. Accordingly, the embryos of O. fusiformis develop first into an enlarged anterior domain that forms larval tissues and the adult head. Notably, this also occurs in the so-called ‘head larvae’ of other bilaterians, with which the O. fusiformis larva shows extensive transcriptomic similarities. Together, our findings suggest that the temporal decoupling of head and trunk formation, as maximally observed in head larvae, facilitated larval evolution in Bilateria. This diverges from prevailing scenarios that propose either co-option or innovation of gene regulatory programmes to explain larva and adult origins. Comparative chromosome-scale genome sequencing and transcriptomic and epigenomic profiling of three different species of annelid provide insight into the evolutionary origin of larvae.
登录
查看更多内容
影响因子：
3.7
作者：
Frobius, Andreas C.;Matus, David Q.;Seaver, Elaine C.
通讯作者：
Seaver, Elaine C.
DOI：
10.1073/pnas.95.22.13062
发表时间：
1998-10-27
影响因子：
11.1
作者：
Arenas-Mena, C;Martinez, P;Davidson, EH
通讯作者：
Davidson, EH
影响因子：
56.9
作者：
DAVIDSON, EH;PETERSON, KJ;CAMERON, RA
通讯作者：
CAMERON, RA
影响因子：
9.3
作者：
Durand NC;Shamim MS;Machol I;Rao SS;Huntley MH;Lander ES;Aiden EL
通讯作者：
Aiden EL
影响因子：
10.7
作者：
Hoang DT;Chernomor O;von Haeseler A;Minh BQ;Vinh LS
通讯作者：
Vinh LS