Association of serum docosahexaenoic acid and eicosapentaenoic acid levels with dietary intakes and supplement use during pregnancy: a prospective observational study.
Association of serum docosahexaenoic acid and eicosapentaenoic acid levels with dietary intakes and supplement use during pregnancy: a prospective observational study.
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DOI：
10.1017/jns.2023.105
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发表时间：
2023
影响因子：
2.5
通讯作者：
Nagamatsu, Takeshi
中科院分区：
文献类型：
--
作者：
Wakabayashi, Nana;Haruna, Megumi;Yonezawa, Kaori;Sasagawa, Emi;Usui, Yuriko;Ohori, Riko;Aoyama, Satoko;Sasaki, Satoshi;Nagamatsu, Takeshi
本研究旨在确定血清二十二碳六烯酸（DHA）和二十碳五烯酸（EPA）水平与妊娠期间膳食摄入量和补充剂使用的关系。这项前瞻性观察性研究在日本东京的一所大学医院进行。在第二和第三个三个月的参与者获得了一份自我管理的问卷，评估了过去一个月DHA和EPA补充剂的使用频率，以及一份自我管理的饮食史问卷。使用气相色谱法分析非空腹血清DHA和EPA水平。使用多重比较分析来确定补充剂使用频率的生物标志物差异，并使用斯皮尔曼相关系数来确定食物组的生物标志物和DHA和EPA摄入量。在116名参与者中，11名（9.5%）在第二个三个月，18名（15.5%）在第三个三个月定期使用补充剂（每周≥5次）。在妊娠中期和晚期，经常使用者的血清DHA和EPA水平高于从未使用者。从鱼类和贝类中摄入的DHA和EPA与中、晚期孕妇的血清DHA和EPA呈正相关。每周补充剂使用≥5次以及鱼类和贝类摄入量与高血清DHA和EPA水平相关。
This study aimed to determine the association of serum docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) levels with dietary intakes and supplement use during pregnancy. This prospective observational study was conducted at a university hospital in Tokyo, Japan. Participants in their second and third trimesters were given a self-administered questionnaire assessing the frequency of DHA and EPA supplement use in the past month and a brief-type self-administered diet history questionnaire. Non-fasting serum DHA and EPA levels were analysed using gas chromatography. Differences in biomarkers by frequency of supplement use were determined using multiple comparison analyses, and Spearman's correlation coefficient was used to determine biomarkers and DHA and EPA intakes by food group. Of the 116 participants, 11 (9⋅5 %) in the second trimester and 18 (15⋅5 %) in the third trimester regularly used supplements (≥5 times per week). Regular users had higher serum DHA and EPA levels than never users in the second and third trimesters. Dietary DHA and EPA intake from fish and shellfish was positively correlated with serum DHA and EPA in the second and third trimesters. Supplement use ≥5 times per week and fish and shellfish intake were associated with high serum DHA and EPA levels.
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影响因子：
5.9
作者：
Aparicio E;Martín-Grau C;Bedmar C;Serrat Orus NS;Basora J;Arija V;The Eclipses Study Group
通讯作者：
The Eclipses Study Group
影响因子：
7.1
作者：
Carlson, Susan E.;Colombo, John;Shaddy, D. Jill
通讯作者：
Shaddy, D. Jill
DOI：
10.1016/j.plefa.2017.11.003
发表时间：
2018-01-01
影响因子：
3
作者：
Stoutjesdijk, E.;Schaafsma, A.;Muskiet, F. A. J.
通讯作者：
Muskiet, F. A. J.
DOI：
10.1080/14767058.2020.1739020
发表时间：
2020-03-13
影响因子：
1.8
作者：
Kikuchi, Daisuke;Obara, Taku;Kuriyama, Shinichi
通讯作者：
Kuriyama, Shinichi
影响因子：
3.2
作者：
Kirk, Sara F. L.;Cade, Janet E.;Conner, Mark
通讯作者：
Conner, Mark