Bridging the Great Divide: What Can Neurology Learn From Psychiatry?
Bridging the Great Divide: What Can Neurology Learn From Psychiatry?
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DOI：
10.1176/appi.neuropsych.17100200
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Price BH
中科院分区：
文献类型：
--
作者：
Perez DL;Keshavan MS;Scharf JM;Boes AD;Price BH
神经病学和精神病学有着共同的历史渊源，并依靠类似的工具来研究大脑疾病。然而，这些临床神经科学的医学和科学方法的实际整合仍然是难以捉摸的。虽然已经写了很多关于需要将新兴的系统水平，细胞分子和遗传表观遗传学的进步纳入精神疾病的心理科学，较少注意到应用临床神经科学原理，使用综合神经生物学，心理学，社会学方法来概念化神经系统疾病。在这篇观点文章中，我们首先简要概述了神经病学和精神病学之间历史上交织和复杂的关系。通过一系列的小插曲，我们然后说明了一些传统的精神疾病是如何被重新概念化的神经发育和意识障碍的一部分。神经病学和精神病学的交叉点通过突出跨越传统诊断边界的条件而进一步强调。我们认为，神经病学和精神病学之间的鸿沟可以缩小从病变为基础的神经精神疾病的理解为基础的电路，从单向到双向模型的脑行为关系，从完全依赖于分类诊断跨诊断维度的角度来看，从筒仓为基础的研究和治疗跨学科的方法。神经学家和精神病学家实施综合临床神经科学方法来评估和管理大脑疾病的时机已经成熟。行为神经学和神经精神病学的子专业有望引领下一代临床医生将脑科学与心理和社会文化因素相结合。这些努力将促进转化研究，振兴培训计划，并推动以患者为中心的有效治疗的发展。
Neurology and psychiatry share common historical origins and rely on similar tools to study brain disorders. Yet, the practical integration of medical and scientific approaches across these clinical neurosciences has remained elusive. While much has been written about the need to incorporate emerging systems-level, cellular-molecular and genetic-epigenetic advances into a science of mind for psychiatric disorders, less attention has been given to applying clinical neuroscience principles to conceptualize neurologic conditions using an integrated neurobio-psycho-social approach. In this perspective article, we first briefly outline the historically interwoven and complicated relationship between neurology and psychiatry. Through a series of vignettes, we then illustrate how some traditional psychiatric conditions are being re-conceptualized in part as disorders of neurodevelopment and awareness. The intersection of neurology and psychiatry is further emphasized by highlighting conditions that cut across traditional diagnostic boundaries. We argue that the divide between neurology and psychiatry can be narrowed by moving from lesion-based toward circuit-based understandings of neuropsychiatric disorders, from unidirectional toward bidirectional models of brain-behavior relationships, from exclusive reliance on categorical diagnoses toward trans-diagnostic dimensional perspectives, and from silo-based research and treatments towards interdisciplinary approaches. The time is now ripe for neurologists and psychiatrists to implement an integrated clinical neuroscience approach to the assessment and management of brain disorders. The subspecialty of Behavioral Neurology & Neuropsychiatry is poised to lead the next generation of clinicians to merge brain science with psychological and social-cultural factors. These efforts will catalyze translational research, revitalize training programs, and advance the development of impactful patient-centered treatments.
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DOI：
10.1176/appi.ajp.2015.14091200
发表时间：
2016-04-01
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Clementz BA;Sweeney JA;Hamm JP;Ivleva EI;Ethridge LE;Pearlson GD;Keshavan MS;Tamminga CA
通讯作者：
Tamminga CA
影响因子：
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作者：
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DOI：
10.1176/appi.neuropsych.18.1.6
发表时间：
2006-12-01
影响因子：
2.9
作者：
Arciniegas, DB;Kaufer, DI
通讯作者：
Kaufer, DI
DOI：
10.1097/00004583-200010000-00014
发表时间：
2000-10-01
影响因子：
13.3
作者：
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通讯作者：
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