Factors influencing the development of otitis media among Sicilian children affected by upper respiratory tract infections.
Factors influencing the development of otitis media among Sicilian children affected by upper respiratory tract infections.
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DOI：
10.1016/j.bjorl.2015.04.002
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发表时间：
2016-03
影响因子：
2.2
通讯作者：
Sireci, Federico
中科院分区：
文献类型：
--
作者：
Martines, Francesco;Salvago, Pietro;Ferrara, Sergio;Messina, Giuseppe;Mucia, Marianna;Plescia, Fulvio;Sireci, Federico
上呼吸道感染是一个非特异性术语，用于描述涉及鼻子，鼻窦，咽和喉的急性感染。儿童上呼吸道感染常伴有咽鼓管功能障碍，并并发中耳炎，中耳内的一种炎症过程。中耳炎的环境、流行病学和家族危险因素（如性别、社会经济和教育因素、吸烟暴露、过敏或母乳喂养持续时间）以前有过报道，但实际上没有关于它们在西西里上呼吸道感染儿童中扩散的数据。探讨西西里岛儿童中耳炎发病的主要危险因素及其有无上呼吸道感染的流行情况。在为期3周的监测期内，204名上呼吸道感染并发中耳炎的儿童和204名年龄和性别匹配的健康对照进行了病例对照研究。通过标准化问卷调查和皮肤试验对17个流行病学相关特征进行了盘点。采用单因素分析和多因素logistic回归分析探讨危险因素与中耳炎发生的关系。中耳炎与家庭规模大、父母受教育程度低、三岁以内受教育程度高相关（p < 0.05）；哮喘、咳嗽、喉咽反流、打鼾、呼吸暂停患儿更易发生中耳炎（p < 0.05）。过敏和城市定位使吸烟儿童中耳炎发病风险分别增加166%和277% (p < 0.05)；在过敏人群中，哮喘和宠物的共同作用使复发风险增加了11%，而过敏、咳嗽和流鼻涕的共同作用使复发风险增加了74%。上呼吸道感染和中耳炎是常见的儿童疾病，与父母受教育程度低（p = 0.0001）、接触烟雾（p = 0.0001）、室内接触霉菌（p = 0.0001）、咽喉反流病（p = 0.0002）和缺乏母乳喂养（p = 0.0014）密切相关；出现过敏、持续咳嗽和流鼻涕时，中耳炎复发的风险增加（p = 0.0001）。应建议修改已确定的中耳炎危险因素，以实现正确的初级保健干预。
Upper respiratory tract infection is a nonspecific term used to describe an acute infection involving the nose, paranasal sinuses, pharynx and larynx. Upper respiratory tract infections in children are often associated with Eustachian tube dysfunction and complicated by otitis media, an inflammatory process within the middle ear. Environmental, epidemiologic and familial risk factors for otitis media (such as sex, socioeconomic and educational factors, smoke exposure, allergy or duration of breastfeeding) have been previously reported, but actually no data about their diffusion among Sicilian children with upper respiratory tract infections are available. To investigate the main risk factors for otitis media and their prevalence in Sicilian children with and without upper respiratory tract infections. A case–control study of 204 children with upper respiratory tract infections who developed otitis media during a 3 weeks monitoring period and 204 age and sex-matched healthy controls. Seventeen epidemiologically relevant features were inventoried by means of standardized questionnaires and skin tests were performed. Univariate analysis and multivariate logistic regression analysis were used to examine the association between risk factors and occurrence of otitis media. Otitis media resulted strongly associated to large families, low parental educational attainment, schooling within the third years of life (p < 0.05); children were more susceptible to develop otitis media in the presence of asthma, cough, laryngopharyngeal reflux disease, snoring and apnea (p < 0.05). Allergy and urban localization increased the risk of otitis media in children exposed to smoke respectively of 166% and 277% (p < 0.05); the joint effect of asthma and presence of pets in allergic population increased the risk of recurrence of 11%, while allergy, cough and runny nose together increased this risk of 74%. Upper respiratory tract infections and otitis media are common childhood diseases strongly associated with low parental educational attainment (p = 0.0001), exposure to smoke (p = 0.0001), indoor exposure to mold (p = 0.0001), laryngopharyngeal reflux disease (p = 0.0002) and the lack of breast-feeding (p = 0.0014); an increased risk of otitis media recurrences was observed in the presence of allergy, persistent cough and runny nose (p = 0.0001). The modification of the identified risk factors for otitis media should be recommended to realize a correct primary care intervention.
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影响因子：
0.9
作者：
Leuwer, R;Koch, U
通讯作者：
Koch, U
影响因子：
15.9
作者：
Bakaletz, Lauren O.
通讯作者：
Bakaletz, Lauren O.
DOI：
10.1016/j.ijporl.2012.09.013
发表时间：
2012-12-01
影响因子：
1.5
作者：
Rupa, V.;Isaac, Rita;Thenmozhi, M.
通讯作者：
Thenmozhi, M.
影响因子：
8
作者：
Revai, Krystal;Dobbs, Laura A.;Chonmaitree, Tasnee
通讯作者：
Chonmaitree, Tasnee
影响因子：
6.4
作者：
TEELE, DW;KLEIN, JO;ROSNER, B
通讯作者：
ROSNER, B