The effect of self-assessed fatigue and subjective cognitive impairment on work capacity: The case of multiple sclerosis.
The effect of self-assessed fatigue and subjective cognitive impairment on work capacity: The case of multiple sclerosis.
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DOI：
10.1177/1352458518769837
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发表时间：
2019-04
期刊：
影响因子：
--
通讯作者：
Jönsson L
中科院分区：
文献类型：
--
作者：
Kobelt G;Langdon D;Jönsson L
多发性硬化症患者的身体残疾对就业的影响有很好的记录，但神经系统症状的影响研究较少。我们调查了自我报告的疲劳和认知困难对工作的独立影响。在一项大型欧洲疾病成本调查中，采用视觉模拟量表（VAS 0-10）评估自我报告的疲劳、主观认知障碍（SCI）和工作效率。该分析控制了国家、年龄、诊断年龄、性别、教育和身体残疾。共有13，796名患者处于工作年龄，6，598名患者正在工作。身体残疾和教育对工作的可能性有着巨大的影响。SCI和疲劳VAS每增加一分，工作概率分别降低8.7%和4.4%（p < 0.0001）。正常工作时间随着疲劳和认知问题严重程度的增加而线性下降，而评估前3个月的病假则增加。最后，这两种症状的严重程度与工作效率受到影响的程度相关（p < 0.0001）。我们的研究结果证实了自我报告的疲劳和SCI对工作能力的独立贡献，并强调了评估在临床实践中的重要性。
The impact of physical disability in multiple sclerosis on employment is well documented but the effect of neurological symptoms has been less well studied. We investigated the independent effect of self-reported fatigue and cognitive difficulties on work. In a large European cost of illness survey, self-reported fatigue, subjective cognitive impairment (SCI), and productivity at work were assessed with visual analogue scales (VAS 0–10). The analysis controlled for country, age, age at diagnosis, gender, education, and physical disability. A total of 13,796 patients were of working age and 6,598 were working. Physical disability had a powerful impact on the probability of working, as did education. The probability of working was reduced by 8.7% and 4.4% for each point increase on the VAS for SCI and fatigue, respectively (p < 0.0001). Regular work hours decreased linearly with increasing severity of fatigue and cognitive problems, while sick leave during the 3 months preceding the assessment increased. Finally, the severity of both symptoms was associated with the level at which productivity at work was affected (p < 0.0001). Our results confirm the independent contribution of self-reported fatigue and SCI on work capacity and highlight the importance of assessment in clinical practice.
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DOI：
10.3233/wor-152200
发表时间：
2015-01-01
影响因子：
2.3
作者：
Bishop, Malachy;Rumrill, Phillip D.
通讯作者：
Rumrill, Phillip D.
影响因子：
3.3
作者：
Incerti, Chiara Concetta;Argento, Ornella;Nocentini, Ugo
通讯作者：
Nocentini, Ugo
影响因子：
--
作者：
Cadden, Margaret;Arnett, Peter
通讯作者：
Arnett, Peter
影响因子：
3
作者：
FISK, JD;PONTEFRACT, A;MURRAY, TJ
通讯作者：
MURRAY, TJ
影响因子：
5.1
作者：
Campbell, J.;Rashid, W.;Langdon, D.
通讯作者：
Langdon, D.