The Multiple Cellular Functions of the Hsp90 Molecular Chaperone: The Role of Hsp90 and the Conserved R2TP Complex in Ribosomal RNA Processing
The Multiple Cellular Functions of the Hsp90 Molecular Chaperone: The Role of Hsp90 and the Conserved R2TP Complex in Ribosomal RNA Processing
批准号:
170401
负责人:
Houry Walid A
金额:
$49.38万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2013-09-01
中文摘要
热休克蛋白90是一种普遍存在于真细菌和真核生物所有分支中的分子伴侣。它在细胞信号传导中起着核心作用,因为它对维持包括类固醇激素受体在内的几种信号蛋白的活性至关重要。
英文摘要
Hsp90 is a ubiquitous molecular chaperone that is found in eubacteria and all branches of eukarya. It plays a central role in cellular signaling since it is essential for maintaining the activity of several signaling proteins including steroid hormone rec
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