Exploiting the self-assembly of hydrophobin proteins to engineer functional nanostructuring surfaces

利用疏水蛋白的自组装来设计功能性纳米结构表面

• 批准号: DP1093949
• 负责人: Prof Margaret Sunde
• 金额: $ 22.99万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-03-12 至 2013-07-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1093949
• 关键词: Exploiting; self; assembly; hydrophobin; proteins

There is an increasing world-wide demand for advanced nano-biomaterials with novel properties. We will use natural hydrophobin proteins to coat nanodevices and make them more compatible with biological systems. Hydrophobin coatings will be applicable to biosensors, medical devices, diagnostics and drug delivery systems. The research will lead to an understanding of the basic mechanisms of protein self-assembly and will have application outcomes that contribute to Australia being an important player in the field of nanotechnology. This is critical for Australia's long term competitiveness and productivity in and beyond the 21st century.

世界范围内对具有新特性的先进纳米生物材料的需求日益增加。我们将使用天然疏水蛋白质来包覆纳米器件，使其与生物系统更相容。疏水蛋白涂层将适用于生物传感器、医疗设备、诊断和药物输送系统。这项研究将有助于了解蛋白质自组装的基本机制，并将产生有助于澳大利亚成为纳米技术领域重要参与者的应用成果。这对澳大利亚在世纪及以后的长期竞争力和生产力至关重要。