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Dissection of molecular pathways involved in controlling tumor-associated inflammation and in mediating interactions with tumor-associated macrophages (TAMs).

Dissection of molecular pathways involved in controlling tumor-associated inflammation and in mediating interactions with tumor-associated macrophages (TAMs).
剖析涉及控制肿瘤相关炎症和介导与肿瘤相关巨噬细胞 (TAM) 相互作用的分子途径。
批准号：
219239
负责人：
Villani Alexandra-Chloe
金额：
$10.2万
依托单位：
Broad Institute of MIT and Harvard (Cambridge, MA)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-11-01 至 2012-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=219239&lang=en
关键词：
Cancer Gene Expression Inflammation Innate Immunity Macrophage State Polarization By Tumor Microarrays Pathway Analyses Pathways Controlling Tumor-Associated Inflammation Shrna Gene Silencing Tumor-Macrophage Coculture

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With the Cancer Trends Progress Report from the National Cancer Institute predicting cancer to be the leading cause of death worldwide in 2010, there is an urgent need to further dissect mechanisms involved in disease progression. Since Rudolf Virchow fir
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