Novel antibacterial targets, assays, probes and opportunities in bacterial cell wall biogenesis

细菌细胞壁生物发生中的新抗菌靶点、检测方法、探针和机会

• 批准号: 219604
• 负责人: Clarke Anthony J
• 金额: --
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-11-01 至 2011-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=219604&lang=en
• 关键词: Antibacterial Peptides; Bacterial Cell Walls Peptidoglycan; Biosynthesis; Enzyme Substrates & Assays; High Throughput Screening; Inhibitors; Maturation; Peptidoglycan; Synthesis

Ever since its discovery and use in the early 1940's, penicillins and other antibiotics that target peptidolgyan in bacterial cell wall biosynthesis have been cornerstones in our fight against infection. Peptidoglycan biosynthesis is thus a well validat

自从 20 世纪 40 年代初发现并使用以来，青霉素和其他针对细菌细胞壁生物合成中肽聚糖的抗生素一直是我们对抗感染的基石。 因此，肽聚糖生物合成是一个很好的验证