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Structure-function relationship of peptidoglycan O-acetyltransferase, a potential new antivirulence target to combat AMR

Structure-function relationship of peptidoglycan O-acetyltransferase, a potential new antivirulence target to combat AMR
肽聚糖O-乙酰转移酶的结构-功能关系,对抗AMR的潜在新抗毒靶点
批准号:
369069
负责人:
Clarke Anthony J
金额:
$44.86万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
翻译
确保其细胞壁的机械强度对细菌的生存能力至关重要。细胞壁的这种强度是由一种称为肽聚糖的细菌特有的连续(大)分子赋予的,肽聚糖完全包裹着细胞。鉴于小恶魔
英文摘要
Ensuring the mechanical strength of their cell walls is essential to the viability of bacteria. This strength to the wall is conferred by a continuous (macro)molecule unique to bacteria called peptidoglycan which completely encases the cell. Given the imp
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Novel antibacterial targets, assays, probes and opportunities in bacterial cell wall biogenesis
  • 批准号:
    223643
  • 项目类别:
    Operating Grants
  • 资助金额:
    $145.7万
  • 财政年份:
    2011
  • 负责人:
    Clarke Anthony J
  • 依托单位:
Novel antibacterial targets, assays, probes and opportunities in bacterial cell wall biogenesis
  • 批准号:
    219604
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2010
  • 负责人:
    Clarke Anthony J
  • 依托单位:
Lytic transglycosylases as new antibacterial targets
  • 批准号:
    179116
  • 项目类别:
    Operating Grants
  • 资助金额:
    $40.52万
  • 财政年份:
    2009
  • 负责人:
    Clarke Anthony J
  • 依托单位:
UKCan-BaCWAN: A bilateral bacterial cell wall biosynthesis network
  • 批准号:
    182401
  • 项目类别:
    Operating Grants
  • 资助金额:
    $4.37万
  • 财政年份:
    2009
  • 负责人:
    Clarke Anthony J
  • 依托单位:
海外基金