Novel antibacterial targets, assays, probes and opportunities in bacterial cell wall biogenesis

细菌细胞壁生物发生中的新抗菌靶点、检测方法、探针和机会

• 批准号: 223643
• 负责人: Clarke Anthony J
• 金额: $ 145.7万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2015-01-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=223643&lang=en
• 关键词: Antibacterial Peptides; Bacterial Cell Walls; Biosynthesis; Enzyme Substrates & Assays; High Throughput Screening; Inhibitors; Maturation; Peptidoglycan; Synthesis

Millions of people die each year from bacterial infections and tens of millions suffer from the consequences of these infections. The discovery of the antibiotic penicillin once opened the door to treat these infections by stopping bacteria making the pol

每年有数百万人死于细菌感染，数千万人遭受这些感染的后果。抗生素盘尼西林的发现，曾一度为通过阻止细菌制造聚合物来治疗这些感染打开了大门。