Glucocorticoid-induced osteoporosis: the role of G protein upregulation in osteoblasts

糖皮质激素诱导的骨质疏松症：G 蛋白上调在成骨细胞中的作用

• 批准号: 226611
• 负责人: Mitchell Jane A
• 金额: $ 43.67万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-03-01 至 2016-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=226611&lang=en
• 关键词: Bone Biology; Osteoblasts; Osteoporosis; Transgenic Animals

Glucocorticoids are widely used drugs in the treatment of inflammatory diseases as well as some forms of cancer. Long-term use of these agents is limited by profound skeletal growth inhibition in children and osteoporosis in both children and adults. We a

糖皮质激素是广泛用于治疗炎症性疾病以及某些形式的癌症的药物。这些药物的长期使用受到儿童严重骨骼生长抑制和儿童及成人骨质疏松症的限制。我们有