Variation in G protein expression in bone cells determines bone quality and response to catabolic and anabolic stimuli

骨细胞中 G 蛋白表达的变化决定骨质量以及对分解代谢和合成代谢刺激的反应

• 批准号: 343253
• 负责人: Mitchell Jane A
• 金额: $ 36.76万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-03-01 至 2019-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=343253&lang=en
• 关键词: Andropause; Bone Fracture; Diet; Exercise; Menopause; Osteoporosis

Poor bone health is a major issue in the aging Canadian population, in which 1 in 3 postmenopausal women and 1 in 6 older men have osteoporosis and half will have a fragility fracture. Hip fracture in people over 65 years of age significantly increases mo

骨质健康状况不佳是加拿大老龄化人口的一个主要问题，其中三分之一的绝经后妇女和六分之一的老年男性患有骨质疏松症，一半患有脆性骨折。65岁以上的人髋部骨折的发病率显著增加