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Mechanisms by which hyperinsulinemia promotes pancreatic cancer

Mechanisms by which hyperinsulinemia promotes pancreatic cancer
高胰岛素血症促进胰腺癌的机制
批准号:
408005
负责人:
Johnson James D
金额:
$79.42万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01

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中文摘要
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英文摘要
High levels of the hormone insulin are a cardinal feature of obesity and early type 2 diabetes, and are induced by unhealthy 'Western diets' high in sugar and fat. It has been suggested that excess insulin contributes to cancer initiation and/or progressi
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Targeting sodium channels for beta-cell protection and insulin secretion in diabetes
  • 批准号:
    477278
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Johnson James D
  • 依托单位:
Beta-cell resilience to insulin-driven stress in type 1 diabetes: Lessons from both sexes
  • 批准号:
    446710
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.73万
  • 财政年份:
    2020
  • 负责人:
    Johnson James D
  • 依托单位:
Mechanisms linking reduced circulating insulin to insulin sensitivity and longevity
  • 批准号:
    408012
  • 项目类别:
    Operating Grants
  • 资助金额:
    $79.42万
  • 财政年份:
    2019
  • 负责人:
    Johnson James D
  • 依托单位:
Regulation of beta-cell proliferation by insulin production workload
  • 批准号:
    356395
  • 项目类别:
    Operating Grants
  • 资助金额:
    $86.94万
  • 财政年份:
    2016
  • 负责人:
    Johnson James D
  • 依托单位:
海外基金