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Regulation of beta-cell proliferation by insulin production workload

Regulation of beta-cell proliferation by insulin production workload
胰岛素产生工作量对 β 细胞增殖的调节
批准号:
356395
负责人:
Johnson James D
金额:
$86.94万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2021-10-01

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中文摘要
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英文摘要
There is an inverse relationship between the functionality of a cell and its ability to proliferate, but the underlying mechanisms are still not clear. Our group has recently demonstrated that normal levels of insulin production in pancreatic beta-cells c
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Targeting sodium channels for beta-cell protection and insulin secretion in diabetes
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    2022
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Beta-cell resilience to insulin-driven stress in type 1 diabetes: Lessons from both sexes
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Mechanisms by which hyperinsulinemia promotes pancreatic cancer
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    408005
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    2019
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Mechanisms linking reduced circulating insulin to insulin sensitivity and longevity
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    408012
  • 项目类别:
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  • 依托单位:
海外基金