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Beta-cell resilience to insulin-driven stress in type 1 diabetes: Lessons from both sexes

Beta-cell resilience to insulin-driven stress in type 1 diabetes: Lessons from both sexes
1 型糖尿病中 β 细胞对胰岛素驱动压力的恢复能力:两性的经验教训
批准号:
446710
负责人:
Johnson James D
金额:
$0.73万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-12-01 至 2021-12-01

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中文摘要
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英文摘要
Type 1 diabetes (T1D), often diagnosed in children, affects >300,000 Canadians. In T1D, the immune system targets and destroys a special type of cell called a beta cell which makes insulin. It is becoming clear that problems within beta cells and changes
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Targeting sodium channels for beta-cell protection and insulin secretion in diabetes
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    477278
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    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Johnson James D
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Mechanisms by which hyperinsulinemia promotes pancreatic cancer
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    408005
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    Operating Grants
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    $79.42万
  • 财政年份:
    2019
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    Johnson James D
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Mechanisms linking reduced circulating insulin to insulin sensitivity and longevity
  • 批准号:
    408012
  • 项目类别:
    Operating Grants
  • 资助金额:
    $79.42万
  • 财政年份:
    2019
  • 负责人:
    Johnson James D
  • 依托单位:
Regulation of beta-cell proliferation by insulin production workload
  • 批准号:
    356395
  • 项目类别:
    Operating Grants
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    $86.94万
  • 财政年份:
    2016
  • 负责人:
    Johnson James D
  • 依托单位:
海外基金