Zebrafish as an in vivo model of vertebrate mast cell development and systemic mastocytosis

斑马鱼作为脊椎动物肥大细胞发育和系统性肥大细胞增多症的体内模型

• 批准号: 190964
• 负责人: Berman Jason N
• 金额: $ 21.5万
• 依托单位: IWK Health Centre (Halifax)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2012-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=190964&lang=en
• 关键词: Mast Cells; Systemic Mastocytosis; Transgenesis; Zebrafish

Mast cells are responsible for many of the symptoms associated with inflammation and allergic reactions, but their development remains controversial. A failure of this process may result in an expansion of abnormal mast cells and a condition called syste

肥大细胞负责许多与炎症和过敏反应相关的症状，但它们的发展仍然存在争议。 这一过程的失败可能会导致异常肥大细胞的扩张和称为系统性肥大细胞增多的情况。