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New insights into mast cell development and contribution to malignant progression - further exploitation of the zebrafish model

New insights into mast cell development and contribution to malignant progression - further exploitation of the zebrafish model
关于肥大细胞发育及其对恶性进展的贡献的新见解——斑马鱼模型的进一步利用
批准号:
267385
负责人:
Berman Jason N
金额:
$41.19万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2016-09-01

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中文摘要
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英文摘要
Mast cells are blood cells involved in allergic reactions, inflammation and contribute to causing some cancers. Normal mast cell development remains unclear. We took advantage of the transparent zebrafish to study normal mast cell development and model a
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Identifying novel strategies for leukemia prevention using zebrafish models of dnajc21-mutant Shwachman Diamond syndrome
Using the zebrafish as a model for chemoprevention for TP53 mutation carriers
  • 批准号:
    401265
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.58万
  • 财政年份:
    2019
  • 负责人:
    Berman Jason N
  • 依托单位:
Molecular interrogation and a small molecule screen of NUP98-HOXA9 induced AML in the zebrafish
  • 批准号:
    234355
  • 项目类别:
    Operating Grants
  • 资助金额:
    $12.27万
  • 财政年份:
    2011
  • 负责人:
    Berman Jason N
  • 依托单位:
Zebrafish as an in vivo model of vertebrate mast cell development and systemic mastocytosis
  • 批准号:
    190964
  • 项目类别:
    Operating Grants
  • 资助金额:
    $21.5万
  • 财政年份:
    2009
  • 负责人:
    Berman Jason N
  • 依托单位:
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