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Exploring novel combinatorial therapies for personalized management of Cystic Fibrosis using primary human airway epithelial cells

Exploring novel combinatorial therapies for personalized management of Cystic Fibrosis using primary human airway epithelial cells
探索利用原代人气道上皮细胞个性化治疗囊性纤维化的新型组合疗法
批准号：
439577
负责人：
Nguyen Jenny P
金额：
$7.65万
依托单位：
McMaster University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-11-01 至 2023-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=439577&lang=en
关键词：
Biomarkers Cell Biology Cell Culture Cystic Fibrosis Diagnostics Drug Discovery - Correctors Drug Discovery - Potentiators Fluorescent Plate-Based Assays Predictors Primary Cells

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中文摘要
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英文摘要
Cystic Fibrosis is the most common genetic condition affecting Canadian newborns (1 in 3600), and is caused by the inheritance of a mutation, from each parent, in the gene for the Cystic Fibrosis transmembrane conductance regulator. People with Cystic Fib
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The role of cystic fibrosis transmembrane conductance regulator in airway surface liquide pH and host defenses in human airway epithelial cells.
  • 批准号：
    474040
  • 项目类别：
    Miscellaneous Programs
  • 资助金额：
    $0.44万
  • 财政年份：
    2022
  • 负责人：
    Nguyen Jenny P
  • 依托单位：
    Leiden University (The Netherlands)
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