New Biomimetic Nanostructured Coatings for Hip Implants

用于髋关节植入物的新型仿生纳米结构涂层

• 批准号: DP1096150
• 负责人: Em/Prof George Simon
• 金额: $ 35.52万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1096150
• 关键词: New; Biomimetic; Nanostructured; Coatings; Hip

Over 30,000 hip implants operations take place in Australia each year, due largely to a significant and growing proportion of the population suffering from conditions such as osteoporosis. The coating on the implants, required to cause good bone ingrowth and adhesion between bone and implant, is far from perfect. We propose to spray coatings which mimic the structure of bone, and thus offer improved mechanical properties such as appropriate rigidity and toughness, and stimulate better bone growth at the interface. In this way the implant should be much longer lasting and the need for undesirable revision surgery reduced. The processing technique proposed could also be a useful platform coating technology in a number of other industries.

澳大利亚每年进行超过30，000例髋关节植入手术，这主要是由于患有骨质疏松症等疾病的人口比例显著增加。植入物上的涂层，需要引起良好的骨长入和骨与植入物之间的粘附，远非完美。我们建议喷涂模拟骨结构的涂层，从而提供改善的机械性能，如适当的刚度和韧性，并刺激界面处更好的骨生长。通过这种方式，植入物应该更持久，并且减少了不期望的翻修手术的需要。所提出的处理技术也可以是许多其他行业中有用的平台涂层技术。