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Characterizing the mechanics of prostate cancer cells as a function of androgen receptor expression, metastatic potential, and microenvironmental stiffness

Characterizing the mechanics of prostate cancer cells as a function of androgen receptor expression, metastatic potential, and microenvironmental stiffness
将前列腺癌细胞的机制表征为雄激素受体表达、转移潜力和微环境硬度的函数
批准号：
458850
负责人：
Molter Clayton W
金额：
$7.65万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-11-01 至 2024-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=458850&lang=en
关键词：
Biophysics Cell Mechanics Cell Motility Epithelial-To-Mesenchymal Transition Intercellular Stress Magnetic Twisting Cytometry Mechanobiology Metastasis Prostate Cancer Traction Force Microscopy

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中文摘要
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英文摘要
Regardless of mutational origin, in all cancers, cells must change their biophysical characteristics to migrate through fibrous multicellular environments. As such, cell softening and increased cell-generated forces are emerging near-universal biomarkers
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Characterizing the cellular mechanics of metastatic prostate cancer progression in response to microenvironment stiffness
  • 批准号：
    428990
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2019
  • 负责人：
    Molter Clayton W
  • 依托单位：
    McGill University
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