Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer.
Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer.
批准号:
477245
负责人:
Aparicio Samuel J
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-10-01 至 2023-10-01
关键词:
中文摘要
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英文摘要
Triple negative breast cancer (TNBC) accounts for ~15% of early breast cancers, and ~75% of TNBCs have poor prognosis. Similarly concerning, high grade serous ovarian cancer (HGSOC) is the most lethal gynecologic malignancy. Both cancers develop drug resi
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Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer
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批准号:477662
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项目类别:Operating Grants
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资助金额:$75.79万
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财政年份:2023
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负责人:Aparicio Samuel J
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依托单位:
Mechanisms and targeting of repair deficient cancers with G-quadruplex small molecule ligands
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批准号:478057
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项目类别:Operating Grants
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资助金额:$76.35万
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财政年份:2023
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负责人:Aparicio Samuel J
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依托单位:
Canada Research Chair - Tier 1
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批准号:459667
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项目类别:
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资助金额:$101.99万
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财政年份:2021
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负责人:Aparicio Samuel J
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依托单位:
Targeting the dynamics and genomics of clonal evolution in cancer patients
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批准号:333653
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项目类别:Operating Grants
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资助金额:$206.42万
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财政年份:2015
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负责人:Aparicio Samuel J
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依托单位:
Canada Research Chair Tier 1
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批准号:332843
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项目类别:
-
资助金额:$101.99万
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财政年份:2014
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负责人:Aparicio Samuel J
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依托单位:
Linking clonal genomes to tumour evolution and therapeutics
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批准号:266702
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项目类别:Operating Grants
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资助金额:$75.8万
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财政年份:2012
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负责人:Aparicio Samuel J
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依托单位:
PP2a protein serine/threonine phosphatase mutations in cancer: functional consequences and clinical relevance
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批准号:238781
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项目类别:Operating Grants
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资助金额:$42.9万
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财政年份:2011
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负责人:Aparicio Samuel J
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依托单位:
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
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批准号:204208
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项目类别:
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资助金额:$36.43万
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财政年份:2009
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负责人:Aparicio Samuel J
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依托单位:
Improving computational inference of single nucleotide variants from next generation sequencing of cancer genomes.
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批准号:182345
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项目类别:Operating Grants
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资助金额:$7.22万
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财政年份:2009
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负责人:Aparicio Samuel J
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依托单位:
海外基金