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Mechanisms and targeting of repair deficient cancers with G-quadruplex small molecule ligands

Mechanisms and targeting of repair deficient cancers with G-quadruplex small molecule ligands
G-四链体小分子配体修复缺陷型癌症的机制和靶向
批准号:
478057
负责人:
Aparicio Samuel J
金额:
$76.35万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-03-01 至 2028-03-01
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中文摘要
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英文摘要
Triple negative breast cancer (TNBC) accounts for ~15% of early breast cancers, and 75% of TNBCs have poor prognoses. Our objective is to lower mortality and morbidity from these and other genomically unstable cancers, by developing therapeutic approaches
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Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer
  • 批准号:
    477662
  • 项目类别:
    Operating Grants
  • 资助金额:
    $75.79万
  • 财政年份:
    2023
  • 负责人:
    Aparicio Samuel J
  • 依托单位:
Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer.
  • 批准号:
    477245
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Aparicio Samuel J
  • 依托单位:
Canada Research Chair - Tier 1
  • 批准号:
    459667
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2021
  • 负责人:
    Aparicio Samuel J
  • 依托单位:
Targeting the dynamics and genomics of clonal evolution in cancer patients
  • 批准号:
    333653
  • 项目类别:
    Operating Grants
  • 资助金额:
    $206.42万
  • 财政年份:
    2015
  • 负责人:
    Aparicio Samuel J
  • 依托单位:
海外基金